日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Enhanced fatty acid oxidation in osteoprogenitor cells provides protection from high-fat diet induced bone dysfunction

骨祖细胞中脂肪酸氧化增强可保护骨骼免受高脂饮食引起的功能障碍。

Ananya Nandy ,Ron C M Helderman ,Santosh Thapa ,Sun H Peck ,Alison Richards ,Shobana Jayapalan ,Nikita Narayani ,Michael P Czech ,Clifford J Rosen ,Elizabeth Rendina-Ruedy

Altered Osteoblast Metabolism with Aging Results in Lipid Accumulation and Oxidative Stress Mediated Bone Loss

随着年龄增长,成骨细胞代谢发生改变,导致脂质积累和氧化应激介导的骨质流失。

Ananya Nandy ,Alison Richards ,Santosh Thapa ,Alena Akhmetshina ,Nikita Narayani ,Elizabeth Rendina-Ruedy

Bone Fragility in High Fat Diet-induced Obesity is Partially Independent of Type 2 Diabetes in Mice

高脂饮食引起的肥胖小鼠的骨质脆弱性与 2 型糖尿病部分无关

Sasidhar Uppuganti #, Amy Creecy #, Daniel Fernandes, Kate Garrett, Kara Donovan, Rafay Ahmed, Paul Voziyan, Elizabeth Rendina-Ruedy, Jeffry S Nyman0

Loss or inhibition of lysosomal acid lipase in vitro leads to cholesteryl ester accumulation without affecting muscle formation or mitochondrial function

体外溶酶体酸性脂肪酶的丧失或抑制会导致胆固醇酯的积累,而不会影响肌肉形成或线粒体功能

Alena Akhmetshina, Laszlo Schooltink, Melina Amor, Katharina B Kuentzel, Silvia Rainer, Ananya Nandy, Hansjoerg Habisch, Tobias Madl, Elizabeth Rendina-Ruedy, Katharina Leithner, Nemanja Vujić, Dagmar Kratky

Lipolysis supports bone formation by providing osteoblasts with endogenous fatty acid substrates to maintain bioenergetic status

脂肪分解通过为成骨细胞提供内源性脂肪酸底物来维持生物能量状态,从而支持骨骼形成。

Ananya Nandy ,Ron C M Helderman ,Santosh Thapa ,Shobana Jayapalan ,Alison Richards ,Nikita Narayani ,Michael P Czech ,Clifford J Rosen ,Elizabeth Rendina-Ruedy

Mitochondrial β-oxidation of adipose-derived fatty acids by osteoblasts fuels parathyroid hormone-induced bone formation

成骨细胞对脂肪来源的脂肪酸进行线粒体β氧化,促进甲状旁腺激素诱导的骨形成

Nathalie S Alekos, Priyanka Kushwaha, Soohyun P Kim, Zhu Li, Abdullah Abood, Naomi Dirckx, Susan Aja, Joe Kodama, Jean G Garcia-Diaz, Satoru Otsuru, Elizabeth Rendina-Ruedy, Michael J Wolfgang, Ryan C Riddle

A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density

3q21.1 的调节变异会增加高血糖和骨密度改变的多效性风险

Nasa Sinnott-Armstrong, Isabel S Sousa, Samantha Laber, Elizabeth Rendina-Ruedy, Simon E Nitter Dankel, Teresa Ferreira, Gunnar Mellgren, David Karasik, Manuel Rivas, Jonathan Pritchard, Anyonya R Guntur, Roger D Cox, Cecilia M Lindgren, Hans Hauner, Richard Sallari, Clifford J Rosen, Yi-Hsiang Hsu,

Metabolic programming determines the lineage-differentiation fate of murine bone marrow stromal progenitor cells

代谢编程决定小鼠骨髓基质祖细胞的谱系分化命运

Michaela Tencerova ,Elizabeth Rendina-Ruedy ,Ditte Neess ,Nils Færgeman ,Florence Figeac ,Dalia Ali ,Morten Danielsen ,Anders Haakonsson ,Clifford J Rosen ,Moustapha Kassem

Progenitor recruitment and adipogenic lipolysis contribute to the anabolic actions of parathyroid hormone on the skeleton

祖细胞募集和脂肪生成脂肪分解促进甲状旁腺激素对骨骼的合成代谢作用

David E Maridas, Elizabeth Rendina-Ruedy, Ron C Helderman, Victoria E DeMambro, Daniel Brooks, Anyonya R Guntur, Beate Lanske, Mary L Bouxsein, Clifford J Rosen

Blocking FSH induces thermogenic adipose tissue and reduces body fat

阻断 FSH 可诱导产热脂肪组织并减少体内脂肪

Peng Liu, Yaoting Ji, Tony Yuen, Elizabeth Rendina-Ruedy, Victoria E DeMambro, Samarth Dhawan, Wahid Abu-Amer, Sudeh Izadmehr, Bin Zhou, Andrew C Shin, Rauf Latif, Priyanthan Thangeswaran, Animesh Gupta, Jianhua Li, Valeria Shnayder, Samuel T Robinson, Yue Eric Yu, Xingjian Zhang, Feiran Yang, Ping