日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Small-molecule strategies to combat antibiotic resistance: mechanisms, modifications, and contemporary approaches

对抗抗生素耐药性的小分子策略：机制、修饰和当代方法

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d5ra04047g
Elkady, Hazem; Salman, Ibtehal Nasser; Khalifa, Mohamed M
发表日期：2025
文献求助 收藏

Discovery of new thiadiazole-based VEGFR-2 inhibitors: design, synthesis, cytotoxicity, and apoptosis induction

新型噻二唑类VEGFR-2抑制剂的发现：设计、合成、细胞毒性和凋亡诱导

期刊:Future Medicinal Chemistry
影响因子:3.4
doi:10.1080/17568919.2025.2552639
Elkaeed, Eslam B; Elgammal, Walid E; Elkady, Hazem; Mahdy, Hazem A; Alsfouk, Aisha A; Husein, Dalal Z; Soliman, Omar A; Omara, Mariam; Eissa, Ibrahim H; Metwaly, Ahmed M
EGFR
毒理研究
凋亡
细胞生物学
表观遗传
VEGF
EGF
发表日期：2025
文献求助 收藏

Development of novel furan-based VEGFR-2 inhibitors and apoptotic inducers for colorectal cancer

开发新型呋喃类VEGFR-2抑制剂和凋亡诱导剂用于结直肠癌治疗

期刊:Future Medicinal Chemistry
影响因子:3.4
doi:10.1080/17568919.2025.2587566
Elkaeed, Eslam B; Al Ward, Maged Mohammed Saleh; Elkady, Hazem; Yousef, Reda G; Elsheshiny, Asmaa A A; Abdelfattah, Shimaa S; El-Fakharany, Esmail M; Alsfouk, Aisha A; Metwaly, Ahmed M; Eissa, Ibrahim H
EGFR
表观遗传
EGF
肿瘤
VEGF
凋亡
肠癌
肿瘤免疫
发表日期：2025
文献求助 收藏

Anti-breast cancer potential of thieno-pyrimidine derivatives as VEGFR-2 inhibitors

噻吩并嘧啶衍生物作为VEGFR-2抑制剂的抗乳腺癌潜力

期刊:Future Medicinal Chemistry
影响因子:3.4
doi:10.1080/17568919.2025.2479422
Alsfouk, Aisha A; Al Ward, Maged Mohammed Saleh; Al-Qadhi, Mustafa A; El-Metwally, Souad A; Yousef, Reda G; Elkaeed, Eslam B; Husein, Dalal Z; Amin, Fatma G; Elkady, Hazem; Metwaly, Ahmed M; Eissa, Ibrahim H
肿瘤
肿瘤免疫
EGF
乳腺癌
EGFR
VEGF
发表日期：2025
文献求助 收藏

Design and synthesis of thiadiazoles as anticancer, apoptotic, and VEGFR-2 inhibitors

噻二唑类化合物的设计与合成及其作为抗癌、凋亡和VEGFR-2抑制剂的应用

期刊:Future Medicinal Chemistry
影响因子:3.4
doi:10.1080/17568919.2025.2485863
Elgammal, Walid E; Elkady, Hazem; Dahab, Mohammed A; Mahdy, Hazem A; Hagras, Mohamed; Nofal, Ahmed; Alsfouk, Bshra A; Elkaeed, Eslam B; Eissa, Ibrahim H; Metwaly, Ahmed M
肿瘤
凋亡
表观遗传
肿瘤免疫
EGF
EGFR
VEGF
发表日期：2025
文献求助 收藏

Integrated in silico and in vitro exploration of the anti-VEGFR-2 activities of a semisynthetic xanthine alkaloid inhibiting breast cancer

结合计算机模拟和体外实验，探索一种抑制乳腺癌的半合成黄嘌呤生物碱的抗VEGFR-2活性

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0316146
Elkaeed, Eslam B; Elkady, Hazem; Khattab, Ahmed M; Yousef, Reda G; Al-Ghulikah, Hanan A; Husein, Dalal Z; Ibrahim, Ibrahim M; Elkady, Mohamed A; Metwaly, Ahmed M; Eissa, Ibrahim H
EGFR
乳腺癌
EGF
肿瘤
VEGF
肿瘤免疫
发表日期：2025
文献求助 收藏

A novel sulfamoylphenyl-dihydro-thiadiazole derivative as a dual EGFR and carbonic anhydrase inhibitor for cancer therapy

一种新型磺酰苯基二氢噻二唑衍生物作为双重EGFR和碳酸酐酶抑制剂用于癌症治疗

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0328305
Eissa, Ibrahim H; Elkady, Hazem; Elgammal, Walid E; Mahdy, Hazem A; Husein, Dalal Z; Amin, Fatma G; Elsheshiny, Asmaa A A; Abdelfattah, Shimaa S; Alsfouk, Aisha A; Elkaeed, Eslam B; Metwaly, Ahmed M
EGF
EGFR
肿瘤
肿瘤免疫
发表日期：2025
文献求助 收藏

Design and synthesis of new nicotinamides as immunomodulatory VEGFR-2 inhibitors and apoptosis inducers

设计和合成新型烟酰胺类化合物作为免疫调节性VEGFR-2抑制剂和细胞凋亡诱导剂

期刊:Future Medicinal Chemistry
影响因子:3.4
doi:10.1080/17568919.2024.2421150
Yousef, Reda G; Eissa, Ibrahim H; Elkady, Hazem; M Mehany, Ahmed B; Abo-Saif, Mariam Ali; Radwan, Mohamed M; ElSohly, Mahmoud A; Ibrahim, Ibrahim M; Elwan, Alaa; El-Zahabi, Mohamed Ayman
EGFR
表观遗传
免疫/内分泌
EGF
VEGF
凋亡
细胞生物学
发表日期：2024
文献求助 收藏

In silico and in vitro evaluation of the anti-virulence potential of patuletin, a natural methoxy flavone, against Pseudomonas aeruginosa

利用计算机模拟和体外实验评估天然甲氧基黄酮类化合物帕图列汀对铜绿假单胞菌的抗毒力潜力

期刊:PeerJ
影响因子:2.4
doi:10.7717/peerj.16826
Metwaly, Ahmed; Saleh, Moustafa M; Alsfouk, Aisha; Ibrahim, Ibrahim M; Abd-Elraouf, Muhamad; Elkaeed, Eslam; Elkady, Hazem; Eissa, Ibrahim
发表日期：2024
文献求助 收藏

Identification of new theobromine-based derivatives as potent VEGFR-2 inhibitors: design, semi-synthesis, biological evaluation, and in silico studies

鉴定新型可可碱衍生物作为强效VEGFR-2抑制剂：设计、半合成、生物学评价和计算机模拟研究

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d3ra04007k
Eissa, Ibrahim H; Yousef, Reda G; Elkady, Hazem; Elkaeed, Eslam B; Alsfouk, Aisha A; Husein, Dalal Z; Ibrahim, Ibrahim M; Elhendawy, Mostafa A; Godfrey, Murrell; Metwaly, Ahmed M
VEGF
EGF
EGFR
发表日期：2023
文献求助 收藏