日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

HiPSC-derived 3D neural models reveal neurodevelopmental pathomechanisms of the Cockayne Syndrome B

HiPSC 衍生的 3D 神经模型揭示了 Cockayne 综合征 B 的神经发育病理机制

Julia Kapr, Ilka Scharkin, Haribaskar Ramachandran, Philipp Westhoff, Marius Pollet, Selina Dangeleit, Gabriele Brockerhoff, Andrea Rossi, Katharina Koch, Jean Krutmann, Ellen Fritsche

Cockayne Syndrome Patient iPSC-Derived Brain Organoids and Neurospheres Show Early Transcriptional Dysregulation of Biological Processes Associated with Brain Development and Metabolism

科凯恩综合征患者 iPSC 衍生的脑类器官和神经球显示与脑发育和代谢相关的生物过程的早期转录失调

Leon-Phillip Szepanowski, Wasco Wruck, Julia Kapr, Andrea Rossi, Ellen Fritsche, Jean Krutmann, James Adjaye

Nanoparticles Dysregulate the Human Placental Secretome with Consequences on Angiogenesis and Vascularization

纳米粒子使人类胎盘分泌蛋白失调,影响血管生成和血管化

Battuja Dugershaw-Kurzer, Jonas Bossart, Marija Buljan, Yvette Hannig, Sarah Zehnder, Govind Gupta, Vera M Kissling, Patrycja Nowak-Sliwinska, Judy R van Beijnum, Arjan W Griffioen, Stefan Masjosthusmann, Etta Zühr, Ellen Fritsche, René Hornung, Thomas Rduch, Tina Buerki-Thurnherr

Application of the adverse outcome pathway concept for investigating developmental neurotoxicity potential of Chinese herbal medicines by using human neural progenitor cells in vitro

应用不良结果途径概念在体外利用人类神经祖细胞研究中草药的发育神经毒性潜力

Jördis Klose #, Lu Li #, Melanie Pahl, Farina Bendt, Ulrike Hübenthal, Christian Jüngst, Patrick Petzsch, Astrid Schauss, Karl Köhrer, Ping Chung Leung, Chi Chiu Wang, Katharina Koch, Julia Tigges, Xiaohui Fan #, Ellen Fritsche #

Molecular and Functional Characterization of Different BrainSphere Models for Use in Neurotoxicity Testing on Microelectrode Arrays

用于微电极阵列神经毒性测试的不同 BrainSphere 模型的分子和功能表征

Julia Hartmann, Noah Henschel, Kristina Bartmann, Arif Dönmez, Gabriele Brockerhoff, Katharina Koch, Ellen Fritsche

Cobalt chloride has beneficial effects across species through a hormetic mechanism

氯化钴通过激素机制对不同物种产生有益作用

Alfonso Schiavi, Alessandra Runci, Teresa Maiorino, Francesco Davide Naso, Marta Barenys, Ellen Fritsche, Flavie Strappazzon, Natascia Ventura

Scientific Validation of Human Neurosphere Assays for Developmental Neurotoxicity Evaluation

人类神经球试验对发育神经毒性评估的科学验证

Katharina Koch, Kristina Bartmann, Julia Hartmann, Julia Kapr, Jördis Klose, Eliška Kuchovská, Melanie Pahl, Kevin Schlüppmann, Etta Zühr, Ellen Fritsche

The Human Induced Pluripotent Stem Cell Test as an Alternative Method for Embryotoxicity Testing

人类诱导性多能干细胞测试作为胚胎毒性测试的替代方法

Saskia Galanjuk, Etta Zühr, Arif Dönmez, Deniz Bartsch, Leo Kurian, Julia Tigges, Ellen Fritsche

Human Induced Pluripotent Stem Cell-Derived Neural Progenitor Cells Produce Distinct Neural 3D In Vitro Models Depending on Alginate/Gellan Gum/Laminin Hydrogel Blend Properties

人类诱导性多能干细胞衍生的神经祖细胞根据海藻酸盐/结冷胶/层粘连蛋白水凝胶共混物的特性产生不同的神经 3D 体外模型

Julia Kapr, Laura Petersilie, Thomas Distler, Ines Lauria, Farina Bendt, Clemens M Sauter, Aldo R Boccaccini, Christine R Rose, Ellen Fritsche

Interaction between magnesium and methylglyoxal in diabetic polyneuropathy and neuronal models

镁与甲基乙二醛在糖尿病性多发性神经病变和神经元模型中的相互作用

Alexander Strom ,Klaus Strassburger ,Martin Schmuck ,Hanna Shevalye ,Eric Davidson ,Fariba Zivehe ,Gidon Bönhof ,Rudolph Reimer ,Bengt-Frederik Belgardt ,Thomas Fleming ,Barbara Biermann ,Volker Burkart ,Karsten Müssig ,Julia Szendroedi ,Mark A Yorek ,Ellen Fritsche ,Peter P Nawroth ,Michael Roden ,Dan Ziegler