In Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission Tomography
LSN3172176 是一种新型 M1 选择性毒蕈碱受体激动剂示踪分子,可用于正电子发射断层扫描,本文对其进行了体外药理学表征和体内验证。
期刊:Journal of Pharmacology and Experimental Therapeutics
影响因子:3.1
doi:10.1124/jpet.117.246454.
Adrian J Mogg ,Thomas Eessalu ,Megan Johnson ,Rebecca Wright ,Helen E Sanger ,Hongling Xiao ,Michael G Crabtree ,Alex Smith ,Ellen M Colvin ,Douglas Schober ,Donald Gehlert ,Cynthia Jesudason ,Paul J Goldsmith ,Michael P Johnson ,Christian C Felder ,Vanessa N Barth ,Lisa M Broad