日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mutant p53 Directs PARP to Regulate Replication Stress and Drive Breast Cancer Metastasis.

突变型 p53 指导 PARP 调节复制压力并驱动乳腺癌转移。

Xiao Gu, Annor George K, Harmon Katherine W, Chavez Valery, Levine Fayola, Ahuno Samuel, Atmane Mohamed I, St Jean Samantha, Madorsky Rowdo Florencia P, Leybengrub Pamella, Gaglio AnnMarie, Ellison Viola, Venkatesh Divya, Sun Siyu, Merghoub Taha, Greenbaum Benjamin, Elemento Olivier, Davis Melissa B, Ogunwobi Olorunseun, Bargonetti Jill

A cancer persistent DNA repair circuit driven by MDM2, MDM4 (MDMX), and mutant p53 for recruitment of MDC1 and 53BP1 on chromatin.

由 MDM2、MDM4 (MDMX) 和突变 p53 驱动的癌症持续性 DNA 修复回路,用于在染色质上募集 MDC1 和 53BP1

Ellison Viola, Polotskaia Alla, Xiao Gu, Leybengrub Pamella, Lee Rusia, Qiu Weigang, Hendrickson Ronald C, Hu Wenwei, Bargonetti Jill