Discovery of 5-Azaquinoxaline Derivatives as Potent and Orally Bioavailable Allosteric SHP2 Inhibitors
发现5-氮杂喹喔啉衍生物作为高效且口服生物利用度高的变构SHP2抑制剂
期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.3c00310
Elsayed, Mohamed S A; Blake, James F; Boys, Mark L; Brown, Eric; Chapsal, Bruno D; Chicarelli, Mark J; Cook, Adam W; Fell, Jay B; Fischer, John P; Hanson, Lauren; Lemieux, Christine; Martinson, Matthew C; McCown, Joseph; McNulty, Oren T; Mejia, Macedonio J; Neitzel, Nickolas A; Otten, Jennifer N; Rodriguez, Martha E; Wilcox, Daniel; Wong, Christina E; Zhou, Yeyun; Hinklin, Ronald J
