Novel di-aryl chalcone derived pyrazole linked to methane sulfonyl pharmacophore as potent selective COX-2 inhibitors; design, synthesis, molecular modeling, in vitro and in vivo anti-inflammatory activities
一种新型二芳基查尔酮衍生的吡唑衍生物，与甲磺酰基药效团相连，作为强效选择性COX-2抑制剂；设计、合成、分子建模、体外和体内抗炎活性研究。
期刊:Future Medicinal Chemistry
影响因子:3.4
doi:10.1080/17568919.2025.2545171
Abd El-Hameed, Abeer M; Lotfallah, Ahmed H; Nemr, Mohamed T M; Abdelhady, Hoda Khalifa; Haredy, Haredy Hassan; Sayed, Ahmed M; Mohamed, Mamdouh F A; Elsayed Abouzed, Deiaa E; Fadaly, Wael A A
