日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PKRxiv: A Best Practice Model for Advancing Pharmacoequity Through Open Pharmacokinetic Data Sharing

PKRxiv:通过开放药代动力学数据共享推进药物公平的最佳实践模型

Atoyebi, Shakir; Venkatasubramanian, Prajith; Akinloye, Abdulafeez; Eniayewu, Oluwasegun; Best, Brookie M; Else, Laura; Olagunju, Adeniyi

Pharmacokinetics of Dolutegravir, nucleoside analogues, and intracellular metabolites using plasma separation cards: A comparative analysis with traditional sampling methods in healthy volunteers

利用血浆分离卡测定多替拉韦、核苷类似物及其细胞内代谢物的药代动力学:与健康志愿者传统采样方法的比较分析

Thompson, Beth; Else, Laura J; Dickinson, Laura; Edick, Stacey; Zyhowski, Ashley; Ho, Ken; Meyn, Leslie; Dilly-Penchala, Sujan; Shaw, Victoria; McGowan, Ian; Khoo, Saye; Brand, Rhonda M

A model-based comparison of dose reduction strategies for fixed-dose dolutegravir-containing regimens

基于模型的固定剂量多替拉韦方案剂量减少策略比较

Dickinson, Laura; Else, Laura; Venter, Willem D F; Boffito, Marta; Brand, Rhonda; Waitt, Catriona; Hill, Andrew; Khoo, Saye

Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults

开发用于治疗蛇咬伤中毒的口服乌尼硫醇方案:一项针对健康肯尼亚成年人的 1 期开放标签剂量递增安全性试验和药代动力学分析

Abouyannis, Michael; Nyambura, Yvonne K; Ngome, Samson; Riako, Debra; Musyoki, Jennifer; Muiruri, Charles; Orindi, Benedict; Else, Laura; Amara, Alieu; Dickinson, Laura; Clare, Rachel H; Albulescu, Laura-Oana; Westhorpe, Adam P; Kool, Jeroen; Adetifa, Ifedayo; Ndungu, Francis M; FitzGerald, Richard; Khoo, Saye; Lalloo, David G; Casewell, Nicholas R; Hamaluba, Mainga

The tear production of tecovirimat in a single hospitalized mpox patient: a pharmacokinetic analysis

替考韦瑞特对一名住院MPOX患者泪液分泌的影响:药代动力学分析

Woolley, Stephen D; Duru, Iheukwumere; Pagano, Luca; Lester, Rebecca; Devine, Karen; Ahmad, Shazaad; Huq, Raqib; Marshall, Suzanne; McLaughlan, Danielle; Lavery, Mark; Challenger, Elizabeth; Else, Laura J; Semple, Malcolm G; Kaye, Stephen; Khoo, Saye H; Beadsworth, Michael B J

A novel LC-MS/MS method for the determination of favipiravir ribofuranosyl-5'-triphosphate (T-705-RTP) in human peripheral mononuclear cells.

一种测定人外周血单核细胞中法匹拉韦核糖呋喃糖基-5'-三磷酸(T-705-RTP)的新型LC-MS/MS方法

Challenger Elizabeth, Dilly-Penchala Sujan, Hale Colin, Fitzgerald Richard, Reynolds Helen, Chiong Justin, Rowland Tim, Fletcher Tom, Khoo Saye, Else Laura

Undeclared pre-exposure or post-exposure prophylaxis (PrEP/PEP) use among syphilis-positive blood donors, England, 2020 to 2021

2020年至2021年英格兰梅毒阳性献血者中未申报的暴露前或暴露后预防(PrEP/PEP)使用情况

Maddox, Victoria; Reynolds, Claire; Amara, Alieu; Else, Laura; Brailsford, Susan R; Khoo, Saye; Harvala, Heli

A randomized clinical trial of on-demand oral pre-exposure prophylaxis does not modulate lymphoid/myeloid HIV target cell density in the foreskin

一项随机临床试验表明,按需口服暴露前预防药物不会调节包皮中淋巴/髓系 HIV 靶细胞的密度。

Rametse, Cosnet L; Webb, Emily L; Herrera, Carolina; Alinde, Berenice; Besethi, Asiphe; Motaung, Bongani; Mbangiwa, Tshepiso; Leach, Lloyd; Sebaa, Shorok; Pillay, Azure-Dee A P; Seiphetlo, Thabiso B; Malhangu, Boitshoko; Petkov, Stefan; Else, Laura; Mugaba, Susan; Namubiru, Patricia; Odoch, Geoffrey; Opoka, Daniel; Serwanga, Jennifer; Ssemata, Andrew S; Kaleebu, Pontiano; Khoo, Saye; Lebina, Limakatso; Martinson, Neil; Chiodi, Francesca; Fox, Julie; Gray, Clive M

Development and validation of an LC-MS/MS method for quantification of favipiravir in human plasma.

建立和验证用于定量分析人血浆中法匹拉韦的LC-MS/MS方法

Challenger Elizabeth, Penchala Sujan Dilly, Hale Colin, Fitzgerald Richard, Walker Lauren, Reynolds Helen, Chiong Justin, Fletcher Tom, Khoo Saye, Else Laura

Application of novel plasma separation filter cards for quantification of nucleoside/nucleotide reverse transcriptase inhibitor di/triphosphates in dried blood spots using LC-MS

应用新型血浆分离滤卡,通过液相色谱-质谱联用技术定量分析干血斑中的核苷/核苷酸逆转录酶抑制剂二磷酸/三磷酸酯。

Thompson, Beth; Dilly-Penchala, Sujan; Amara, Alieu; Reynolds, Helen; Khoo, Saye; Else, Laura