Elseginy相关文献与解析，生知库 | 链接生命科学的每一步

Identifying and characterising promising small molecule inhibitors of kinesin spindle protein using ligand-based virtual screening, molecular docking, molecular dynamics and MM‑GBSA calculations

使用基于配体的虚拟筛选、分子对接、分子动力学和 MM-GBSA 计算来识别和表征有前景的纺锤体蛋白小分子抑制剂

期刊:Journal of Computer-Aided Molecular Design

影响因子:3

doi:10.1007/s10822-024-00553-5

Anti-Alzheimer activity of new coumarin-based derivatives targeting acetylcholinesterase inhibition

新型香豆素衍生物靶向乙酰胆碱酯酶抑制的抗阿尔茨海默病活性

期刊:RSC Advances

影响因子:4.6

doi:10.1039/d3ra02344c

Kamel, Nahla N; Aly, Hanan F; Fouad, Ghadha I; Abd El-Karim, Somaia S; Anwar, Manal M; Syam, Yasmin M; Elseginy, Samia A; Ahmed, Kawkab A; Booles, Hoda F; Shalaby, Mohamed B; Khalil, Wagdy K B; Sandhir, Rajat; Deshwal, Sonam; Rizk, Maha Z

阿尔茨海默症

发表日期：2023

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Identification and validation of novel microtubule suppressors with an imidazopyridine scaffold through structure-based virtual screening and docking

通过基于结构的虚拟筛选和对接鉴定和验证具有咪唑并吡啶支架的新型微管抑制剂

期刊:RSC Medicinal Chemistry

影响因子:4.1

doi:10.1039/d1md00392e

Samia A Elseginy, A Sofia F Oliveira, Deborah K Shoemark, Richard B Sessions

Promising anti-SARS-CoV-2 drugs by effective dual targeting against the viral and host proteases

通过有效双重靶向病毒和宿主蛋白酶，有望开发出抗SARS-CoV-2药物。

期刊:Bioorganic & Medicinal Chemistry Letters

影响因子:2.2

doi:10.1016/j.bmcl.2021.128099

Elseginy, Samia A; Fayed, Bahgat; Hamdy, Rania; Mahrous, Noura; Mostafa, Ahmed; Almehdi, Ahmed M; S M Soliman, Sameh

Design, Synthesis and Evaluation of New Bioactive Oxadiazole Derivatives as Anticancer Agents Targeting Bcl-2

设计、合成和评价新型生物活性噁二唑衍生物作为靶向Bcl-2的抗癌药物

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms21238980

Hamdy, Rania; Elseginy, Samia A; Ziedan, Noha I; El-Sadek, Mohamed; Lashin, Elsaid; Jones, Arwyn T; Westwell, Andrew D

Selective inhibition of Rhizopus eumelanin biosynthesis by novel natural product scaffold-based designs caused significant inhibition of fungal pathogenesis

通过基于天然产物支架的新型设计选择性抑制根霉真黑色素生物合成，可显著抑制真菌的致病作用

期刊:Biochemical Journal

影响因子:4.4

doi:10.1042/BCJ20200310

Sameh S M Soliman #, Rania Hamdy #, Samia A Elseginy, Teclegiorgis Gebremariam, Alshaimaa M Hamoda, Mohamed Madkour, Thenmozhi Venkatachalam, Mai N Ershaid, Mohammad G Mohammad, Georgios Chamilos, Ashraf S Ibrahim

微生物学

发表日期：2020

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Design and synthesis of new drugs inhibitors of Candida albicans hyphae and biofilm formation by upregulating the expression of TUP1 transcription repressor gene

通过上调TUP1转录抑制基因表达设计合成白色念珠菌菌丝和生物膜形成新药抑制剂

期刊:European Journal of Pharmaceutical Sciences

影响因子:4.3

doi:10.1016/j.ejps.2020.105327

Rania Hamdy, Sameh S M Soliman, Abrar I Alsaadi, Bahgat Fayed, Alshaimaa M Hamoda, Samia A Elseginy, Mohamed I Husseiny, Ashraf S Ibrahim

微生物学

发表日期：2020

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Role of Penile Girth and Length in the Erect State in Reassuring Patients with Small Penis Anxiety

阴茎勃起状态下的周长和长度在缓解小阴茎焦虑患者情绪中的作用

Design, Synthesis, and Antimicrobial Evaluation of New Thiopyrimidine-Benzenesulfonamide Compounds

新型硫代嘧啶-苯磺酰胺化合物的设计、合成及抗菌活性评价

Identifying and characterising promising small molecule inhibitors of kinesin spindle protein using ligand-based virtual screening, molecular docking, molecular dynamics and MM‑GBSA calculations

使用基于配体的虚拟筛选、分子对接、分子动力学和 MM-GBSA 计算来识别和表征有前景的纺锤体蛋白小分子抑制剂

Anti-Alzheimer activity of new coumarin-based derivatives targeting acetylcholinesterase inhibition

新型香豆素衍生物靶向乙酰胆碱酯酶抑制的抗阿尔茨海默病活性

Identification and validation of novel microtubule suppressors with an imidazopyridine scaffold through structure-based virtual screening and docking

通过基于结构的虚拟筛选和对接鉴定和验证具有咪唑并吡啶支架的新型微管抑制剂

Promising anti-SARS-CoV-2 drugs by effective dual targeting against the viral and host proteases

通过有效双重靶向病毒和宿主蛋白酶，有望开发出抗SARS-CoV-2药物。

Design, Synthesis and Evaluation of New Bioactive Oxadiazole Derivatives as Anticancer Agents Targeting Bcl-2

设计、合成和评价新型生物活性噁二唑衍生物作为靶向Bcl-2的抗癌药物

Selective inhibition of Rhizopus eumelanin biosynthesis by novel natural product scaffold-based designs caused significant inhibition of fungal pathogenesis

通过基于天然产物支架的新型设计选择性抑制根霉真黑色素生物合成，可显著抑制真菌的致病作用

Design and synthesis of new drugs inhibitors of Candida albicans hyphae and biofilm formation by upregulating the expression of TUP1 transcription repressor gene

通过上调TUP1转录抑制基因表达设计合成白色念珠菌菌丝和生物膜形成新药抑制剂