日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Babesia divergens host cell egress is mediated by essential and druggable kinases and proteases

巴贝虫(Babesia divergens)宿主细胞的释放是由必需且可药物靶向的激酶和蛋白酶介导的。

Elsworth, Brendan; Keroack, Caroline D; Rezvani, Yasaman; Paul, Aditya S; Barazorda, Keare A; Bauer, Niel C; Tennessen, Jacob A; Sack, Samantha A; Moreira, Cristina K; Gubbels, Marc-Jan; Meyers, Marvin J; Zarringhalam, Kourosh; Duraisingh, Manoj T

The essential genome of Plasmodium knowlesi reveals determinants of antimalarial susceptibility.

诺氏疟原虫的基本基因组揭示了抗疟药物敏感性的决定因素

Elsworth Brendan, Ye Sida, Dass Sheena, Tennessen Jacob A, Sultana Qudseen, Thommen Basil T, Paul Aditya S, Kanjee Usheer, Grüring Christof, Ferreira Marcelo U, Gubbels Marc-Jan, Zarringhalam Kourosh, Duraisingh Manoj T

Sialyl-T Antigen: A Novel Red Blood Cell Determinant for Plasmodium falciparum Invasion

唾液酸-T抗原:一种新型的恶性疟原虫入侵红细胞决定因子

Mikdar, Mahmoud; Shabani, Estela; Grüring, Christof; Chaand, Mudit; Kanjee, Usheer; Goldberg, Jonathan M; Azouzi, Slim; Tennessen, Jacob A; Elsworth, Brendan; Keutcha, Cyrianne; Barteneva, Natasha S; Doench, John G; Duraisingh, Manoj T

PTEX helps efficiently traffic haemoglobinases to the food vacuole in Plasmodium falciparum

PTEX有助于将血红酶高效地运输到恶性疟原虫的食物泡中。

Jonsdottir, Thorey K; Elsworth, Brendan; Cobbold, Simon; Gabriela, Mikha; Ploeger, Ellen; Parkyn Schneider, Molly; Charnaud, Sarah C; Dans, Madeline G; McConville, Malcolm; Bullen, Hayley E; Crabb, Brendan S; Gilson, Paul R

Comparative chemical genomics in Babesia species identifies the alkaline phosphatase phoD as a novel determinant of resistance

巴贝虫属的比较化学基因组学研究发现,碱性磷酸酶phoD是其耐药性的一个新的决定因素。

Keroack, Caroline D; Elsworth, Brendan; Tennessen, Jacob A; Paul, Aditya S; Hua, Renee; Ramirez-Ramirez, Luz; Ye, Sida; Moreira, Cristina M; Meyers, Marvin J; Zarringhalam, Kourosh; Duraisingh, Manoj T

Comparative single-cell transcriptional atlases of Babesia species reveal conserved and species-specific expression profiles

巴贝虫属物种的单细胞转录组比较图谱揭示了保守和物种特异性的表达谱

Rezvani, Yasaman; Keroack, Caroline D; Elsworth, Brendan; Arriojas, Argenis; Gubbels, Marc-Jan; Duraisingh, Manoj T; Zarringhalam, Kourosh

A framework for signaling throughout the life cycle of Babesia species

巴贝斯虫属物种生命周期信号传导框架

Elsworth, Brendan; Duraisingh, Manoj T

Extensive Shared Chemosensitivity between Malaria and Babesiosis Blood-Stage Parasites

疟疾和巴贝虫病血液期寄生虫之间存在广泛的共同化学敏感性

Paul, Aditya S; Moreira, Cristina K; Elsworth, Brendan; Allred, David R; Duraisingh, Manoj T

Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum

鉴定能够双重靶向恶性疟原虫血液期新通透性途径和二氢乳清酸脱氢酶的抑制剂

Dickerman, Benjamin K; Elsworth, Brendan; Cobbold, Simon A; Nie, Catherine Q; McConville, Malcolm J; Crabb, Brendan S; Gilson, Paul R

Plasmodium falciparum transfected with ultra bright NanoLuc luciferase offers high sensitivity detection for the screening of growth and cellular trafficking inhibitors

用超高亮度NanoLuc荧光素酶转染的恶性疟原虫可实现高灵敏度检测,用于筛选生长和细胞运输抑制剂。

Azevedo, Mauro F; Nie, Catherine Q; Elsworth, Brendan; Charnaud, Sarah C; Sanders, Paul R; Crabb, Brendan S; Gilson, Paul R