日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Charting the multilevel molecular response to palbociclib in ER-positive breast cancer

绘制 ER 阳性乳腺癌对 palbociclib 的多层次分子反应图谱

Kavalipati, Archishma; Aponte, Amy; Sullivan, Michael E; Whittington, Sarah L; Martínez, José C; Goda, Grant A; Aleman, Maria M; Emanuele, Michael J; Dominguez, Daniel

USP37 prevents unscheduled replisome unloading through MCM complex deubiquitination.

USP37 通过 MCM 复合物去泛素化防止非计划的复制体卸载

Bolhuis Derek L, Fleifel Dalia, Bonacci Thomas, Wang Xianxi, Mouery Brandon L, Cook Jeanette Gowen, Brown Nicholas G, Emanuele Michael J

Structural mechanism for the recognition of E2F1 by the ubiquitin ligase adaptor Cyclin F

泛素连接酶衔接蛋白细胞周期蛋白F识别E2F1的结构机制

Ngoi, Peter; Wang, Xianxi; Putta, Sivasankar; Da Luz, Ricardo F; Serrão, Vitor Hugo B; Emanuele, Michael J; Rubin, Seth M

Onvansertib exhibits anti-proliferative and anti-invasive effects in endometrial cancer.

Onvansertib 对子宫内膜癌具有抗增殖和抗侵袭作用

Sinha Nikita, Shen Xiaochang, Haag Jennifer, Chen Shuning, Zhang Haomeng, John Catherine, Sun Wenchuan, Emanuele Michael, Zhou Chunxiao, Bae-Jump Victoria

DIG-DUBs: mechanisms and functions of ISG15 deconjugation by human and viral cross-reactive ubiquitin proteases

DIG-DUBs:人类和病毒交叉反应性泛素蛋白酶对ISG15去结合的机制和功能

Bonacci, Thomas; Emanuele, Michael J

Mechanisms of USP18 specificity toward ISG15 revealed by paralog sequence analysis comparison.

通过旁系同源序列分析比较揭示 USP18 对 ISG15 的特异性机制

Bonacci Thomas, Bolhuis Derek L, Brown Nicholas G, Emanuele Michael J

Onvansertib inhibits cell proliferation and increases sensitivity to paclitaxel in uterine serous cancer cells

Onvansertib可抑制子宫浆液性癌细胞增殖并提高其对紫杉醇的敏感性。

Haag, Jennifer G; Shen, Xiaochang; Sinha, Nikita; Chen, Shuning; Deng, Boer; Zhang, Haomeng; John, Catherine; Sun, Wenchuan; Emanuele, Michael; Zhou, Chunxiao; Bae-Jump, Victoria

Charting the Multi-level Molecular Response to Palbociclib in ER-Positive Breast Cancer

绘制 ER 阳性乳腺癌对帕博西尼的多层次分子反应图谱

Kavalipati, Archishma; Aponte, Amy; Sullivan, Michael E; Whittington, Sarah L; Martínez, José C; Goda, Grant; Aleman, Maria M; Emanuele, Michael J; Dominguez, Daniel

Structural mechanism for recognition of E2F1 by the ubiquitin ligase adaptor Cyclin F.

泛素连接酶衔接蛋白细胞周期蛋白F识别E2F1的结构机制

Ngoi Peter, Wang Xianxi, Putta Sivasankar, Da Luz Ricardo F, Serrão Vitor Hugo B, Emanuele Michael J, Rubin Seth M

Structural basis of NSD2 degradation via targeted recruitment of SCF-FBXO22.

通过靶向募集 SCF-FBXO22 实现 NSD2 降解的结构基础

Robertson Kevin C, Amann Sascha J, Liu Tongkun, Funk Adam V, Wang Xianxi, Grishkovskaya Irina, Tabor John R, Norris-Drouin Jacqueline L, Arrowsmith Cheryl H, Collins Jon L, Emanuele Michael J, Haselbach David, James Lindsey I, Brown Nicholas Gene