日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A conserved opal termination codon optimizes a temperature-dependent trade-off between protein production and processing in alphaviruses

保守的蛋白石终止密码子优化了甲病毒中蛋白质生产和加工之间温度依赖性的权衡。

Bhattacharya, Tamanash; Alleman, Eva M; Freeman, Tiia S; Noyola, Alexander C; Emerman, Michael; Malik, Harmit S

Heterozygous and generalist MxA super-restrictors overcome breadth-specificity trade-offs in antiviral restriction.

杂合子和广谱 MxA 超级限制器克服了抗病毒限制中的广度-特异性权衡

Geiger Rechel A, Khera Damini, Tenthorey Jeannette L, Kochs Georg, Graf Laura, Emerman Michael, Malik Harmit S

Antiviral Mx proteins have an ancient origin and widespread distribution among eukaryotes

抗病毒Mx蛋白起源古老,广泛分布于真核生物中。

Langley, Caroline A; Dietzen, Peter A; Emerman, Michael; Tenthorey, Jeannette L; Malik, Harmit S

Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations

插入/缺失突变使抗病毒蛋白能够进化出错义突变无法实现的功能新颖性。

Tenthorey, Jeannette L; Del Banco, Serena; Ramzan, Ishrak; Klingenberg, Hayley; Liu, Chang; Emerman, Michael; Malik, Harmit S

APOBEC3G Antagonism by Vif, or When Structure Meets Biological and Evolutionary Studies

Vif对APOBEC3G的拮抗作用,或当结构与生物学和进化研究相遇

Li, Yen-Li; Langley, Caroline A; Emerman, Michael; Gross, John D

Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal

整合复合物亚基12敲除克服了HIV潜伏逆转的转录阻滞

Gray, Carley N; Ashokkumar, Manickam; Janssens, Derek H; Kirchherr, Jennifer L; Allard, Brigitte; Hsieh, Emily; Hafer, Terry L; Archin, Nancie M; Browne, Edward P; Emerman, Michael

CARD8 inflammasome activation during HIV-1 cell-to-cell transmission

HIV-1细胞间传播过程中CARD8炎症小体的激活

Kulsuptrakul, Jessie; Emerman, Michael; Mitchell, Patrick S

A targeted CRISPR screen identifies ETS1 as a regulator of HIV-1 latency.

有针对性的 CRISPR 筛选发现 ETS1 是 HIV-1 潜伏期的调节因子

Ashokkumar Manickam, Hafer Terry L, Felton Abby, Archin Nancie M, Margolis David M, Emerman Michael, Browne Edward P

Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal

整合复合物亚基12敲除克服了HIV潜伏逆转的转录阻滞

Gray, Carley N; Ashokkumar, Manickam; Janssens, Derek H; Kirchherr, Jennifer; Allard, Brigitte; Hsieh, Emily; Hafer, Terry L; Archin, Nancie M; Browne, Edward P; Emerman, Michael

The Sindbis virus nsP3 opal codon protects viral RNA and fitness by maintaining replication spherule integrity

辛德毕斯病毒nsP3蛋白石密码子通过维持复制球体的完整性来保护病毒RNA和病毒适应性。

Bhattacharya, Tamanash; Freeman, Tiia S; Alleman, Eva M; Wang, Fang; Chechik, Lyuba; Emerman, Michael; Myles, Kevin M; Malik, Harmit S