日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IgG Binding Characteristics of Rhesus Macaque FcγR

恒河猴FcγR的IgG结合特性

Ying N Chan, Austin W Boesch, Nana Y Osei-Owusu, Ali Emileh, Andrew R Crowley, Sarah L Cocklin, Samantha L Finstad, Caitlyn H Linde, Rebecca A Howell, Isaac Zentner, Simon Cocklin, Adam R Miles, Joshua W Eckman, Galit Alter, Joern E Schmitz, Margaret E Ackerman

Covalent conjugation of a peptide triazole to HIV-1 gp120 enables intramolecular binding site occupancy

肽三唑与 HIV-1 gp120 的共价结合可实现分子内结合位点占据

Ali Emileh, Caitlin Duffy, Andrew P Holmes, Arangassery Rosemary Bastian, Rachna Aneja, Ferit Tuzer, Srivats Rajagopal, Huiyuan Li, Cameron F Abrams, Irwin M Chaiken

A model of peptide triazole entry inhibitor binding to HIV-1 gp120 and the mechanism of bridging sheet disruption

肽三唑进入抑制剂与HIV-1 gp120结合的模型及桥接片破坏机制

Ali Emileh, Ferit Tuzer, Herman Yeh, Muddegowda Umashankara, Diogo R M Moreira, Judith M Lalonde, Carole A Bewley, Cameron F Abrams, Irwin M Chaiken

Interactions of peptide triazole thiols with Env gp120 induce irreversible breakdown and inactivation of HIV-1 virions

肽三唑硫醇与 Env gp120 的相互作用诱导 HIV-1 病毒体不可逆分解和失活

Arangassery Rosemary Bastian, Mark Contarino, Lauren D Bailey, Rachna Aneja, Diogo Rodrigo Magalhaes Moreira, Kevin Freedman, Karyn McFadden, Caitlin Duffy, Ali Emileh, George Leslie, Jeffrey M Jacobson, James A Hoxie, Irwin Chaiken

A mechanism by which binding of the broadly neutralizing antibody b12 unfolds the inner domain α1 helix in an engineered HIV-1 gp120

广谱中和抗体 b12 结合后,可使工程化 HIV-1 gp120 的内部结构域 α1 螺旋展开的机制

Emileh, Ali; Abrams, Cameron F