日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection

亲和力成熟的同型相互作用诱导了一系列影响疟疾感染保护的PfCSP结构

Gregory M Martin, Jonathan L Torres, Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Grace Gibson, Re'em Moskovitz, Nathan Beutler, Diana D Jung, Jeffrey Copps, Wen-Hsin Lee, Gonzalo Gonzalez-Paez, Daniel Emerling, Randall S MacGill, Emily Locke, C Richter King, Fidel Zavala, Ian A Wilson, And

Safety, tolerability, and immunogenicity of inactivated poliovirus vaccine with or without E.coli double mutant heat-labile toxin (dmLT) adjuvant in healthy adults; a phase 1 randomized study

灭活脊髓灰质炎病毒疫苗在健康成人中含或不含大肠杆菌双突变耐热毒素 (dmLT) 佐剂的安全性、耐受性和免疫原性;一项 1 期随机研究

Rahsan Erdem, Ilse De Coster, Kanchanamala Withanage, Laina D Mercer, Arnaud Marchant, Martin Taton, Nathalie Cools, Eva Lion, Fred Cassels, Deborah Higgins, Karen Ivinson, Emily Locke, Kutub Mahmood, Peter F Wright, Chris Gast, Jessica A White, Margaret E Ackerman, Jennifer L Konopka-Anstadt, Berna

Extending the range of Plasmodium falciparum transmission blocking antibodies

扩大恶性疟原虫传播阻断抗体的范围

Lacy M Simons, Patricia Ferrer, Nita Gombakomba, Knashka Underwood, Raul Herrera, David L Narum, Gaspar Canepa, Festus Acquah, Linda Amoah, Patrick E Duffy, Carolina Barillas-Mury, Carole Long, Shwu-Maan Lee, Emily Locke, Kazutoyo Miura, Kim C Williamson

Heterologous Expression and Evaluation of Novel Plasmodium falciparum Transmission Blocking Vaccine Candidates

新型恶性疟原虫传播阻断疫苗候选物的异源表达与评价

Roos M de Jong,Susheel K Singh,Karina Teelen,Marga van de Vegte-Bolmer,Geert-Jan van Gemert,Will J R Stone,Emily Locke,Jordan Plieskatt,Michael Theisen,Teun Bousema,Matthijs M Jore

A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum

一种具有抗恶性疟原虫保护活性的抗体靶向的新型 CSP C 端表位

Nathan Beutler, Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Randall S MacGill, Elijah Garcia, Jaeson Calla, Mara Parren, Linlin Yang, Wayne Volkmuth, Emily Locke, Jason A Regules, Sheetij Dutta, Daniel Emerling, Angela M Early, Daniel E Neafsey, Elizabeth A Winzeler, C Richter King, Fidel

Vaccine co-display of CSP and Pfs230 on liposomes targeting two Plasmodium falciparum differentiation stages

针对恶性疟原虫两个分化阶段的脂质体上 CSP 和 Pfs230 疫苗共同展示

Wei-Chiao Huang, Moustafa T Mabrouk, Luwen Zhou, Minami Baba, Mayumi Tachibana, Motomi Torii, Eizo Takashima, Emily Locke, Jordan Plieskatt, C Richter King, Camila H Coelho, Patrick E Duffy, Carole Long, Takafumi Tsuboi, Kazutoyo Miura, Yimin Wu, Tomoko Ishino, Jonathan F Lovell

Plasmodium falciparum Pf77 and male development gene 1 as vaccine antigens that induce potent transmission-reducing antibodies

恶性疟原虫 Pf77 和雄性发育基因 1 作为疫苗抗原可诱导强效的减少传播的抗体

Abhai K Tripathi, Miranda S Oakley, Nitin Verma, Godfree Mlambo, Hong Zheng, Scott M Meredith, Edward Essuman, Ankit Puri, Richard A Skelton, Kazuyo Takeda, Victoria Majam, Isabella A Quakyi, Emily Locke, Merribeth Morin, Kazutoyo Miura, Carole A Long, Sanjai Kumar

Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum

抗NANP抗体的结构和生物物理相关性与体内对恶性疟原虫的保护作用

Tossapol Pholcharee ,David Oyen ,Yevel Flores-Garcia ,Gonzalo Gonzalez-Paez ,Zhen Han ,Katherine L Williams ,Wayne Volkmuth ,Daniel Emerling ,Emily Locke ,C Richter King ,Fidel Zavala ,Ian A Wilson

Monoclonal antibodies block transmission of genetically diverse Plasmodium falciparum strains to mosquitoes

单克隆抗体可阻止遗传多样的恶性疟原虫菌株向蚊子传播

Roos M de Jong #, Lisette Meerstein-Kessel #, Dari F Da, Sandrine Nsango, Joseph D Challenger, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Elias Duarte, Noam Teyssier, Robert W Sauerwein, Thomas S Churcher, Roch K Dabire, Isabelle Morlais, Emily Locke, Martijn A Huynen, Teun Bousema, Matthijs M

Diverse Antibody Responses to Conserved Structural Motifs in Plasmodium falciparum Circumsporozoite Protein

对恶性疟原虫环子孢子蛋白中保守结构基序的不同抗体反应

Tossapol Pholcharee, David Oyen, Jonathan L Torres, Yevel Flores-Garcia, Gregory M Martin, Gonzalo E González-Páez, Daniel Emerling, Wayne Volkmuth, Emily Locke, C Richter King, Fidel Zavala, Andrew B Ward, Ian A Wilson