日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia

异二聚体细胞因子受体的不同组装体调控白血病干细胞程序

Winnie L Kan # ,Urmi Dhagat # ,Kerstin B Kaufmann # ,Timothy R Hercus # ,Tracy L Nero # ,Andy G X Zeng # ,John Toubia # ,Emma F Barry ,Sophie E Broughton ,Guillermo A Gomez ,Brooks A Benard ,Mara Dottore ,Karen S Cheung Tung Shing ,Héléna Boutzen ,Saumya E Samaraweera ,Kaylene J Simpson ,Liqing Jin ,Gregory J Goodall ,C Glenn Begley ,Daniel Thomas ,Paul G Ekert ,Denis Tvorogov ,Richard J D'Andrea ,John E Dick ,Michael W Parker ,Angel F Lopez

A dual role for the N-terminal domain of the IL-3 receptor in cell signalling

IL-3 受体 N 端结构域在细胞信号传导中的双重作用

Sophie E Broughton, Timothy R Hercus, Tracy L Nero, Winnie L Kan, Emma F Barry, Mara Dottore, Karen S Cheung Tung Shing, Craig J Morton, Urmi Dhagat, Matthew P Hardy, Nicholas J Wilson, Matthew T Downton, Christine Schieber, Timothy P Hughes, Angel F Lopez, Michael W Parker

Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis

JAK 活化环磷酸化的积累与骨髓纤维化中的 I 型 JAK 抑制剂戒断综合征有关

Denis Tvorogov, Daniel Thomas, Nicholas P D Liau, Mara Dottore, Emma F Barry, Maya Lathi, Winnie L Kan, Timothy R Hercus, Frank Stomski, Timothy P Hughes, Vinay Tergaonkar, Michael W Parker, David M Ross, Ravindra Majeti, Jeffrey J Babon, Angel F Lopez

The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities

人类 GM-CSF 自身抗体抑制 GM-CSF 的机制提示了新的治疗机会

Urmi Dhagat, Timothy R Hercus, Sophie E Broughton, Tracy L Nero, Karen S Cheung Tung Shing, Emma F Barry, Christy A Thomson, Steve Bryson, Emil F Pai, Barbara J McClure, John W Schrader, Angel F Lopez, Michael W Parker

Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival

磷酸肌醇 3-激酶的蛋白激酶活性调节细胞因子依赖性细胞存活

Daniel Thomas, Jason A Powell, Benjamin D Green, Emma F Barry, Yuefang Ma, Joanna Woodcock, Stephen Fitter, Andrew C W Zannettino, Stuart M Pitson, Timothy P Hughes, Angel F Lopez, Peter R Shepherd, Andrew H Wei, Paul G Ekert, Mark A Guthridge

Fibroblast growth factor receptor 2 phosphorylation on serine 779 couples to 14-3-3 and regulates cell survival and proliferation

成纤维细胞生长因子受体 2 在丝氨酸 779 上的磷酸化与 14-3-3 偶联并调节细胞存活和增殖

Ana Lonic, Emma F Barry, Cindy Quach, Bostjan Kobe, Neil Saunders, Mark A Guthridge