Integrated Assessment of Diclofenac Biotransformation, Pharmacokinetics, and Omics-Based Toxicity in a Three-Dimensional Human Liver-Immunocompetent Coculture System
在三维人肝-免疫活性共培养系统中对双氯芬酸的生物转化、药代动力学和组学毒性进行综合评估
期刊:Drug Metabolism and Disposition
影响因子:4.4
doi:10.1124/dmd.116.074005
Ujjal Sarkar ,Kodihalli C Ravindra ,Emma Large ,Carissa L Young ,Dinelia Rivera-Burgos ,Jiajie Yu ,Murat Cirit ,David J Hughes ,John S Wishnok ,Douglas A Lauffenburger ,Linda G Griffith ,Steven R Tannenbaum
