日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Impact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology

肝脏特异性存活运动神经元 (SMN) 耗竭对中枢神经系统和外周组织病理学的影响

Monique Marylin Alves de Almeida, Yves De Repentigny, Sabrina Gagnon, Emma R Sutton, Rashmi Kothary

Optimization of base editors for the functional correction of SMN2 as a treatment for spinal muscular atrophy

优化碱基编辑器,用于功能性校正 SMN2 以治疗脊髓性肌萎缩症

Christiano R R Alves, Leillani L Ha, Rebecca Yaworski, Emma R Sutton, Cicera R Lazzarotto, Kathleen A Christie, Aoife Reilly, Ariane Beauvais, Roman M Doll, Demitri de la Cruz, Casey A Maguire, Kathryn J Swoboda, Shengdar Q Tsai, Rashmi Kothary, Benjamin P Kleinstiver

Liver SMN restoration rescues the Smn2B/- mouse model of spinal muscular atrophy

肝脏 SMN 修复挽救了 Smn2B/- 小鼠脊髓性肌萎缩症模型

Emma R Sutton, Ariane Beauvais, Rebecca Yaworski, Yves De Repentigny, Aoife Reilly, Monique Marylin Alves de Almeida, Marc-Olivier Deguise, Kathy L Poulin, Robin J Parks, Bernard L Schneider, Rashmi Kothary

Exercise, disease state and sex influence the beneficial effects of Fn14-depletion on survival and muscle pathology in the SOD1G93A amyotrophic lateral sclerosis (ALS) mouse model

运动、疾病状态和性别会影响 Fn14 耗竭对 SOD1G93A 肌萎缩侧索硬化症 (ALS) 小鼠模型的生存和肌肉病理的有益影响

Gareth Hazell, Eve McCallion, Nina Ahlskog, Emma R Sutton, Magnus Okoh, Emad I H Shaqoura, Joseph M Hoolachan, Taylor Scaife, Sara Iqbal, Amarjit Bhomra, Anna J Kordala, Frederique Scamps, Cedric Raoul, Matthew J A Wood, Melissa Bowerman

A transcriptomics-based drug repositioning approach to identify drugs with similar activities for the treatment of muscle pathologies in spinal muscular atrophy (SMA) models

基于转录组学的药物重新定位方法,用于识别具有类似活性的药物,用于治疗脊髓性肌萎缩 (SMA) 模型中的肌肉病变

Joseph M Hoolachan, Eve McCallion, Emma R Sutton, Özge Çetin, Paloma Pacheco-Torres, Maria Dimitriadi, Suat Sari, Gavin J Miller, Magnus Okoh, Lisa M Walter, Peter Claus, Matthew J A Wood, Daniel P Tonge, Melissa Bowerman

Dysregulation of Tweak and Fn14 in skeletal muscle of spinal muscular atrophy mice

脊髓性肌萎缩症小鼠骨骼肌中 Tweak 和 Fn14 的失调

Katharina E Meijboom, Emma R Sutton, Eve McCallion, Emily McFall, Daniel Anthony, Benjamin Edwards, Sabrina Kubinski, Ines Tapken, Ines Bünermann, Gareth Hazell, Nina Ahlskog, Peter Claus, Kay E Davies, Rashmi Kothary, Matthew J A Wood, Melissa Bowerman