Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model
在SARS-CoV-2攻击的雪貂模型中,预防性鼻内给予TLR2/6激动剂可减少上呼吸道病毒脱落。
期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2020.103153
Proud, Pamela C; Tsitoura, Daphne; Watson, Robert J; Chua, Brendon Y; Aram, Marilyn J; Bewley, Kevin R; Cavell, Breeze E; Cobb, Rebecca; Dowall, Stuart; Fotheringham, Susan A; Ho, Catherine M K; Lucas, Vanessa; Ngabo, Didier; Rayner, Emma; Ryan, Kathryn A; Slack, Gillian S; Thomas, Stephen; Wand, Nadina I; Yeates, Paul; Demaison, Christophe; Zeng, Weiguang; Holmes, Ian; Jackson, David C; Bartlett, Nathan W; Mercuri, Francesca; Carroll, Miles W