日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes

雌激素仅影响拥有两条X染色体的人类中类别转换记忆B细胞的频率。

Hannah Peckham ,Anna Radziszewska ,Justyna Sikora ,Nina M de Gruijter ,Restuadi Restuadi ,Melissa Kartawinata ,Lucia Martin-Gutierrez ,George A Robinson ,Claire T Deakin ,Lucy R Wedderburn ,Elizabeth C Jury ,Gary Butler ,Emma S Chambers ,Elizabeth C Rosser # ,Coziana Ciurtin #

Influence of individuals' determinants including vaccine type on cellular and humoral responses to SARS-CoV-2 vaccination

个体因素(包括疫苗类型)对SARS-CoV-2疫苗接种后细胞和体液免疫反应的影响

Emma S Chambers # ,Weigang Cai # ,Giulia Vivaldi ,David A Jolliffe ,Natalia Perdek ,Wenhao Li ,Sian E Faustini ,Joseph M Gibbons ,Corinna Pade ,Alex G Richter ,Anna K Coussens ,Adrian R Martineau

Recruitment of inflammatory monocytes by senescent fibroblasts inhibits antigen-specific tissue immunity during human aging

衰老成纤维细胞募集炎性单核细胞可抑制人类衰老过程中的抗原特异性组织免疫

Emma S Chambers #, Milica Vukmanovic-Stejic #, Barbara B Shih, Hugh Trahair, Priya Subramanian, Oliver P Devine, James Glanville, Derek Gilroy, Malcolm H A Rustin, Tom C Freeman, Neil A Mabbott, Arne N Akbar

Sestrins induce natural killer function in senescent-like CD8+ T cells

Sestrins 诱导衰老样 CD8+ T 细胞的自然杀伤功能

Branca I Pereira #, Roel P H De Maeyer #, Luciana P Covre #, Djamel Nehar-Belaid #, Alessio Lanna, Sophie Ward, Radu Marches, Emma S Chambers, Daniel C O Gomes, Natalie E Riddell, Mala K Maini, Vitor H Teixeira, Samuel M Janes, Derek W Gilroy, Anis Larbi, Neil A Mabbott, Duygu Ucar, George A Kuchel,

Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition

衰老细胞通过 HLA-E 介导的 NK 和 CD8+ T 细胞抑制逃避免疫清除

Branca I Pereira, Oliver P Devine, Milica Vukmanovic-Stejic, Emma S Chambers, Priya Subramanian, Neil Patel, Alex Virasami, Neil J Sebire, Veronica Kinsler, Alexis Valdovinos, Claude Jourdan LeSaux, João F Passos, Antony Antoniou, Malcom H A Rustin, Judith Campisi, Arne N Akbar

Human CD8+ EMRA T cells display a senescence-associated secretory phenotype regulated by p38 MAPK

人类 CD8+ EMRA T 细胞表现出由 p38 MAPK 调控的衰老相关分泌表型

Lauren A Callender, Elizabeth C Carroll, Robert W J Beal, Emma S Chambers, Sussan Nourshargh, Arne N Akbar, Sian M Henson

Impact of Zostavax Vaccination on T-Cell Accumulation and Cutaneous Gene Expression in the Skin of Older Humans After Varicella Zoster Virus Antigen-Specific Challenge

Zostavax 疫苗接种对老年人水痘带状疱疹病毒抗原特异性攻击后皮肤中 T 细胞积聚和皮肤基因表达的影响

Neil P Patel, Milica Vukmanovic-Stejic, Mayte Suarez-Farinas, Emma S Chambers, Daisy Sandhu, Judilyn Fuentes-Duculan, Neil A Mabbott, Malcolm H A Rustin, James Krueger, Arne N Akbar

Distinct endotypes of steroid-resistant asthma characterized by IL-17A(high) and IFN-γ(high) immunophenotypes: Potential benefits of calcitriol

以 IL-17A(高)和 IFN-γ(高)免疫表型为特征的类固醇抵抗性哮喘的不同内型:骨化三醇的潜在益处

Emma S Chambers, Alexandra M Nanzer, Paul E Pfeffer, David F Richards, Peter M Timms, Adrian R Martineau, Christopher J Griffiths, Christopher J Corrigan, Catherine M Hawrylowicz

1α,25-dihydroxyvitamin D3 acts via transforming growth factor-β to up-regulate expression of immunosuppressive CD73 on human CD4+ Foxp3- T cells

1α,25-二羟基维生素 D3 通过转化生长因子-β 上调人类 CD4+ Foxp3- T 细胞上免疫抑制 CD73 的表达

Elizabeth H Mann, Emma S Chambers, Yin-Huai Chen, David F Richards, Catherine M Hawrylowicz

1α,25-dihydroxyvitamin D3 in combination with transforming growth factor-β increases the frequency of Foxp3⁺ regulatory T cells through preferential expansion and usage of interleukin-2

1α,25-二羟基维生素 D3 与转化生长因子-β 结合,通过优先扩增和使用白细胞介素-2 来增加 Foxp3⁺ 调节性 T 细胞的频率

Emma S Chambers, Duangchan Suwannasaen, Elizabeth H Mann, Zoe Urry, David F Richards, Ganjana Lertmemongkolchai, Catherine M Hawrylowicz