日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Phosphodiesterase-4 Inhibition Reduces Cutaneous Inflammation and IL-1β Expression in a Psoriasiform Mouse Model but Does Not Inhibit Inflammasome Activation

磷酸二酯酶-4 抑制剂可减少银屑病小鼠模型中的皮肤炎症和 IL-1β 表达,但不会抑制炎症小体活化

Barbara Meier-Schiesser, Mark Mellett, Marigdalia K Ramirez-Fort, Julia-Tatjana Maul, Annika Klug, Nicola Winkelbeiner, Gabriele Fenini, Peter Schafer, Emmanuel Contassot, Lars E French

IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes

IL-36γ 驱动 EGFR/MEK 抑制和共生痤疮杆菌引起的皮肤毒性

Takashi K Satoh, Mark Mellett, Barbara Meier-Schiesser, Gabriele Fenini, Atsushi Otsuka, Hans-Dietmar Beer, Tamara Rordorf, Julia-Tatjana Maul, Jürg Hafner, Alexander A Navarini, Emmanuel Contassot, Lars E French

Divergent LAG-3 versus BTLA, TIGIT, and FCRL3 expression in Sézary syndrome

Sézary 综合征中 LAG-3 与 BTLA、TIGIT 和 FCRL3 表达存在差异

Florian Anzengruber, Desislava Ignatova, Tanja Schlaepfer, Yun-Tsan Chang, Lars E French, Steve Pascolo, Emmanuel Contassot, Malgorzata Bobrowicz, Wolfram Hoetzenecker, Emmanuella Guenova

Microcrystalline Tyrosine and Aluminum as Adjuvants in Allergen-Specific Immunotherapy Protect from IgE-Mediated Reactivity in Mouse Models and Act Independently of Inflammasome and TLR Signaling

微晶酪氨酸和铝作为过敏原特异性免疫疗法中的佐剂,可在小鼠模型中保护机体免受 IgE 介导的反应性,并且独立于炎症小体和 TLR 信号传导发挥作用

Deborah S Leuthard, Agathe Duda, Sandra N Freiberger, Sina Weiss, Isabella Dommann, Gabriele Fenini, Emmanuel Contassot, Matthias F Kramer, Murray A Skinner, Thomas M Kündig, Matthew D Heath, Pål Johansen

NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22

NLRP3酪氨酸磷酸化受蛋白酪氨酸磷酸酶PTPN22的调控。

Marianne R Spalinger, Stephanie Kasper, Claudia Gottier, Silvia Lang, Kirstin Atrott, Stephan R Vavricka, Sylvie Scharl, Tina Raselli, Isabelle Frey-Wagner, Petrus M Gutte, Markus G Grütter, Hans-Dietmar Beer, Emmanuel Contassot, Andrew C Chan, Xuezhi Dai, David J Rawlings, Florian Mair, Burkhard Becher, Werner Falk, Michael Fried, Gerhard Rogler, Michael Scharl

Tumour hypoxia promotes melanoma growth and metastasis via High Mobility Group Box-1 and M2-like macrophages

肿瘤缺氧通过高迁移率族蛋白B1和M2样巨噬细胞促进黑色素瘤的生长和转移

Roman Huber ,Barbara Meier ,Atsushi Otsuka ,Gabriele Fenini ,Takashi Satoh ,Samuel Gehrke ,Daniel Widmer ,Mitchell P Levesque ,Joanna Mangana ,Katrin Kerl ,Christoffer Gebhardt ,Hiroko Fujii ,Chisa Nakashima ,Yumi Nonomura ,Kenji Kabashima ,Reinhard Dummer ,Emmanuel Contassot ,Lars E French

TNF-α and IFN-γ are potential inducers of Fas-mediated keratinocyte apoptosis through activation of inducible nitric oxide synthase in toxic epidermal necrolysis

TNF-α 和 IFN-γ 是中毒性表皮坏死松解症中通过激活诱导型一氧化氮合酶而导致 Fas 介导的角质形成细胞凋亡的潜在诱导剂

Isabelle Viard-Leveugle, Olivier Gaide, Dragana Jankovic, Laurence Feldmeyer, Katrin Kerl, Chris Pickard, Stéphanie Roques, Peter S Friedmann, Emmanuel Contassot, Lars E French

Resistance to FasL and tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in Sezary syndrome T-cells associated with impaired death receptor and FLICE-inhibitory protein expression

Sezary 综合征 T 细胞对 FasL 和肿瘤坏死因子相关凋亡诱导配体介导的凋亡的抵抗与死亡受体受损和 FLICE 抑制蛋白表达有关

Emmanuel Contassot, Katrin Kerl, Stéphanie Roques, Ryan Shane, Olivier Gaide, Marc Dupuis, Alain H Rook, Lars E French