NAD+ consumption by PARP1 in response to DNA damage triggers metabolic shift critical for damaged cell survival
DNA 损伤导致 PARP1 消耗 NAD+,引发代谢转变,这对受损细胞的存活至关重要
期刊:Molecular Biology of the Cell
影响因子:3.1
doi:10.1091/mbc.E18-10-0650
Michael M Murata, Xiangduo Kong, Emmanuel Moncada, Yumay Chen, Hiromi Imamura, Ping Wang, Michael W Berns, Kyoko Yokomori, Michelle A Digman