日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lung ILC2s are activated in BALB/c mice born to immunized mothers despite complete protection against respiratory syncytial virus

尽管免疫母鼠所产的BALB/c小鼠对呼吸道合胞病毒具有完全保护作用,但其肺部ILC2细胞仍被激活。

Kosanovich, Jessica L; Eichinger, Katherine M; Lipp, Madeline A; Gidwani, Sonal V; Brahmbhatt, Devarshi; Yondola, Mark A; Chi, David H; Perkins, Timothy N; Empey, Kerry M

Recent advances in the prevention of respiratory syncytial virus in pediatrics

儿童呼吸道合胞病毒预防的最新进展

Lipp, Madeline A; Empey, Kerry M

RAGE contributes to allergen driven severe neutrophilic airway inflammation via NLRP3 inflammasome activation in mice

在小鼠中,RAGE 通过激活 NLRP3 炎症小体促进过敏原驱动的严重中性粒细胞性气道炎症。

Killian, Katherine N; Kosanovich, Jessica L; Lipp, Madeline A; Empey, Kerry M; Oury, Tim D; Perkins, Timothy N

Exacerbated lung inflammation following secondary RSV exposure is CD4+ T cell-dependent and is not mitigated in infant BALB/c mice born to PreF-vaccinated dams

二次感染呼吸道合胞病毒后加剧的肺部炎症依赖于 CD4+ T 细胞,并且在接种 PreF 疫苗的母鼠所生的 BALB/c 幼鼠中并未减轻。

Kosanovich, Jessica L; Eichinger, Katherine M; Lipp, Madeline A; Gidwani, Sonal V; Brahmbhatt, Devarshi; Yondola, Mark A; Perkins, Timothy N; Empey, Kerry M

Editorial: Neonatal host immune responses to pulmonary infections

社论:新生儿对肺部感染的宿主免疫反应

Empey, Kerry M; Fixman, Elizabeth D; Cormier, Stephania; Kolls, Jay K; Piedimonte, Giovanni

Prior respiratory syncytial virus infection reduces vaccine-mediated Th2-skewed immunity, but retains enhanced RSV F-specific CD8 T cell responses elicited by a Th1-skewing vaccine formulation

既往呼吸道合胞病毒感染会降低疫苗介导的Th2型免疫反应,但仍能维持由Th1型疫苗制剂诱导的增强的RSV F蛋白特异性CD8 T细胞反应。

Eichinger, Katherine M; Kosanovich, Jessica L; Perkins, Timothy N; Oury, Tim D; Petrovsky, Nikolai; Marshall, Christopher P; Yondola, Mark A; Empey, Kerry M

Strategies for active and passive pediatric RSV immunization

儿童呼吸道合胞病毒主动和被动免疫策略

Eichinger, Katherine M; Kosanovich, Jessica L; Lipp, Madeline; Empey, Kerry M; Petrovsky, Nikolai

Prefusion RSV F Immunization Elicits Th2-Mediated Lung Pathology in Mice When Formulated With a Th2 (but Not a Th1/Th2-Balanced) Adjuvant Despite Complete Viral Protection

尽管病毒完全保护,但当使用 Th2 佐剂(而非 Th1/Th2 平衡佐剂)配制融合前 RSV F 免疫时,小鼠仍会诱发 Th2 介导的肺部病理。

Eichinger, Katherine M; Kosanovich, Jessica L; Gidwani, Sonal V; Zomback, Aaron; Lipp, Madeline A; Perkins, Timothy N; Oury, Tim D; Petrovsky, Nikolai; Marshall, Christopher P; Yondola, Mark A; Empey, Kerry M

Maternal immunization with adjuvanted RSV prefusion F protein effectively protects offspring from RSV challenge and alters innate and T cell immunity

母体接种佐剂型呼吸道合胞病毒(RSV)融合前F蛋白可有效保护后代免受RSV感染,并改变先天免疫和T细胞免疫。

Eichinger, Katherine M; Kosanovich, Jessica L; Lipp, Madeline A; Perkins, Timothy N; Petrovsky, Nikolai; Marshall, Christopher; Yondola, Mark A; Empey, Kerry M

Formulation of the prefusion RSV F protein with a Th1/Th2-balanced adjuvant provides complete protection without Th2-skewed immunity in RSV-experienced young mice

将RSV融合前F蛋白与Th1/Th2平衡佐剂配制,可在RSV感染过的幼鼠中提供完全保护,且不会引起Th2型免疫反应。

Kosanovich, Jessica L; Eichinger, Katherine M; Lipp, Madeline A; Yondola, Mark A; Perkins, Timothy N; Empey, Kerry M