日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A model of zymogen factor XII: insights into protease activation

酶原因子 XII 的模型:对蛋白酶激活的深入理解

Shamanaev, Aleksandr; Ma, Yujie; Ponczek, Michal B; Sun, Mao-Fu; Cheng, Quifang; Dickeson, S Kent; McCarty, Owen J T; Emsley, Jonas; Mohammed, Bassem M; Gailani, David

Crystal structure of coagulation factor XII N-terminal domains 1-5

凝血因子XII N端结构域1-5的晶体结构

Saleem, Muhammad; Li, Chan; Kaira, Bubacarr G; Brown, Alexander K; Pathak, Monika; Najmudin, Shabir; Cowieson, Nathan; Dreveny, Ingrid; Wilson, Clare; Shamanaev, Aleksandr; Gailani, David; Smith, Stephanie A; Morrissey, James H; Philippou, Helen; Emsley, Jonas

Conformational activation and inhibition of von Willebrand factor by targeting its autoinhibitory module

通过靶向其自身抑制模块来激活和抑制血管性血友病因子构象

Arce, Nicholas A; Markham-Lee, Zoe; Liang, Qian; Najmudin, Shabir; Legan, Emily R; Dean, Gabrielle; Su, Ally J; Wilson, Moriah S; Sidonio, Robert F; Lollar, Pete; Emsley, Jonas; Li, Renhao

Epithelial Interleukin-1 Receptor-Like-1 Activation Is Contingent on Interleukin-33 Isoforms and Asthma-Related Receptor Variation.

上皮细胞白细胞介素-1受体样-1的激活取决于白细胞介素-33同工型和哮喘相关受体变异

Portelli Michael A, Ketelaar Maria E, Bates Stewart, Csomor Eszter, Shaw Dominick, Emsley Jonas, Brightling Christopher, Hall Ian, Affleck Karen, Edwards Matthew, Nawijn Martijn C, Koppelman Gerard H, Van Oosterhout Antoon J, Sayers Ian

High molecular weight kininogen interactions with the homologs prekallikrein and factor XI: importance to surface-induced coagulation

高分子量激肽原与同源物前激肽释放酶和因子XI的相互作用:对表面诱导凝血的重要性

Mohammed, Bassem M; Sun, Mao-Fu; Cheng, Qiufang; Litvak, Maxim; McCrae, Keith R; Emsley, Jonas; McCarty, Owen J T; Gailani, David

Conformational analysis and interaction of the Staphylococcus aureus transmembrane peptidase AgrB with its AgrD propeptide substrate

金黄色葡萄球菌跨膜肽酶AgrB与其AgrD前肽底物的构象分析和相互作用

Bardelang, Philip; Murray, Ewan J; Blower, Isobel; Zandomeneghi, Sara; Goode, Alice; Hussain, Rohanah; Kumari, Divya; Siligardi, Giuliano; Inoue, Katsuaki; Luckett, Jeni; Doutch, James; Emsley, Jonas; Chan, Weng C; Hill, Philip; Williams, Paul; Bonev, Boyan B

Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity

泛素特异性蛋白酶11与工程化底物模拟物复合物的结构揭示了去泛素化选择性的分子特征

Maurer, Sigrun K; Mayer, Matthias P; Ward, Stephanie J; Boudjema, Sana; Halawa, Mohamed; Zhang, Jiatong; Caulton, Simon G; Emsley, Jonas; Dreveny, Ingrid

Proteolytic activity of contact factor zymogens

接触因子酶原的蛋白水解活性

Shamanaev, Aleksandr; Emsley, Jonas; Gailani, David

The evolution of factor XI and the kallikrein-kinin system

因子XI和激肽释放酶-激肽系统的演变

Ponczek, Michał B; Shamanaev, Aleksandr; LaPlace, Alec; Dickeson, S Kent; Srivastava, Priyanka; Sun, Mao-Fu; Gruber, Andras; Kastrup, Christian; Emsley, Jonas; Gailani, David

Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa

鉴定出新型高效 PqsR 拮抗剂作为浮游和生物膜生长铜绿假单胞菌群体感应抑制剂

Soukarieh, Fadi; Liu, Ruiling; Romero, Manuel; Roberston, Shaun N; Richardson, William; Lucanto, Simone; Oton, Eduard Vico; Qudus, Naim Ruhul; Mashabi, Alaa; Grossman, Scott; Ali, Sadiqur; Sou, Tomás; Kukavica-Ibrulj, Irena; Levesque, Roger C; Bergström, Christel A S; Halliday, Nigel; Mistry, Shailesh N; Emsley, Jonas; Heeb, Stephan; Williams, Paul; Cámara, Miguel; Stocks, Michael J