Myeloid cell-specific mutation of Spi1 selectively reduces M2-biased macrophage numbers in skeletal muscle, reduces age-related muscle fibrosis and prevents sarcopenia
Spi1 的髓系细胞特异性突变选择性地减少骨骼肌中 M2 偏向的巨噬细胞数量,减少与年龄相关的肌肉纤维化并预防肌肉减少症
期刊:Aging Cell
影响因子:8
doi:10.1111/acel.13690
Ying Wang, Steven S Welc, Michelle Wehling-Henricks, Ying Kong, Connor Thomas, Enca Montecino-Rodriguez, Kenneth Dorshkind, James G Tidball