日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PD1 Blockade Enhances ICAM1-Directed CAR T Therapeutic Efficacy in Advanced Thyroid Cancer

PD1 阻断可增强 ICAM1 靶向 CAR-T 治疗晚期甲状腺癌的疗效

Katherine D Gray #, Jaclyn E McCloskey #, Yogindra Vedvyas #, Olivia R Kalloo, Steve El Eshaky, Yanping Yang, Enda Shevlin, Marjan Zaman, Timothy M Ullmann, Heng Liang, Dessislava Stefanova, Paul J Christos, Theresa Scognamiglio, Andrew B Tassler, Rasa Zarnegar, Thomas J Fahey 3rd, Moonsoo M Jin, Ir

Micromolar affinity CAR T cells to ICAM-1 achieves rapid tumor elimination while avoiding systemic toxicity

微摩尔亲和力CAR-T细胞对ICAM-1实现快速消除肿瘤,同时避免全身毒性

Spencer Park, Enda Shevlin, Yogindra Vedvyas, Marjan Zaman, Susan Park, Yen-Michael S Hsu, Irene M Min, Moonsoo M Jin

Longitudinal PET imaging demonstrates biphasic CAR T cell responses in survivors

纵向PET成像显示幸存者体内CAR T细胞反应呈双相性

Yogindra Vedvyas ,Enda Shevlin ,Marjan Zaman ,Irene M Min ,Alejandro Amor-Coarasa ,Spencer Park ,Susan Park ,Keon-Woo Kwon ,Turner Smith ,Yonghua Luo ,Dohyun Kim ,Young Kim ,Benedict Law ,Richard Ting ,John Babich ,Moonsoo M Jin

The TIR-domain containing adaptor TRAM is required for TLR7 mediated RANTES production

含有 TIR 结构域的接头蛋白 TRAM 是 TLR7 介导的 RANTES 产生所必需的

Enda Shevlin, Sinéad M Miggin

TRIF-mediated TLR3 and TLR4 signaling is negatively regulated by ADAM15

TRIF 介导的 TLR3 和 TLR4 信号传导受到 ADAM15 的负向调控

Suaad Ahmed, Ashwini Maratha, Aisha Qasim Butt, Enda Shevlin, Sinead M Miggin