A cholesterol-binding bacterial toxin provides a strategy for identifying a specific Scap inhibitor that blocks lipid synthesis in animal cells
一种能结合胆固醇的细菌毒素为鉴定一种特异性的Scap抑制剂提供了一种策略,该抑制剂可以阻断动物细胞中的脂质合成。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2318024121
Xu, Shimeng; Smothers, Jared C; Rye, Daphne; Endapally, Shreya; Chen, Hong; Li, Shili; Liang, Guosheng; Kinnebrew, Maia; Rohatgi, Rajat; Posner, Bruce A; Radhakrishnan, Arun