日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Improved PIEZO1 agonism through 4-benzoic acid modification of Yoda1

通过对 Yoda1 进行 4-苯甲酸修饰来提高 PIEZO1 的激动作用

Gregory Parsonage, Kevin Cuthbertson, Naima Endesh, Nicoletta Murciano, Adam J Hyman, Charlotte H Revill, Oleksandr V Povstyan, Eulashini Chuntharpursat-Bon, Marjolaine Debant, Melanie J Ludlow, Timothy Simon Futers, Laeticia Lichtenstein, Jacob A Kinsella, Fiona Bartoli, Maria Giustina Rotordam, Na

Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress

PIEZO1 和 TRPV4 在肝门静脉中具有独立的内皮功能,且 PIEZO1 在机械和渗透压应激中占主导地位。

Endesh, Naima; Chuntharpursat-Bon, Eulashini; Revill, Charlotte; Yuldasheva, Nadira Y; Futers, T Simon; Parsonage, Gregory; Humphreys, Neil; Adamson, Antony; Morley, Lara C; Cubbon, Richard M; Prasad, K Raj; Foster, Richard; Lichtenstein, Laeticia; Beech, David J

Novel Paracrine Action of Endothelium Enhances Glucose Uptake in Muscle and Fat

内皮细胞的新型旁分泌作用增强肌肉和脂肪组织对葡萄糖的摄取

Viswambharan, Hema; Yuldasheva, Nadira Y; Imrie, Helen; Bridge, Katherine; Haywood, Natalie J; Skromna, Anna; Hemmings, Karen E; Clark, Emily R; Gatenby, V Kate; Cordell, Paul; Simmons, Katie J; Makava, Natallia; Abudushalamu, Yilizila; Endesh, Naima; Brown, Jane; Walker, Andrew M N; Futers, Simon T; Porter, Karen E; Cubbon, Richard M; Naseem, Khalid; Shah, Ajay M; Beech, David J; Wheatcroft, Stephen B; Kearney, Mark T; Sukumar, Piruthivi

Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells

剪切应力激活 ADAM10 脱落酶,通过内皮细胞中的 Piezo1 力传感器调节 Notch1

Vincenza Caolo #, Marjolaine Debant #, Naima Endesh, T Simon Futers, Laeticia Lichtenstein, Fiona Bartoli, Gregory Parsonage, Elizabeth Av Jones, David J Beech

Yoda1 analogue (Dooku1) which antagonizes Yoda1-evoked activation of Piezo1 and aortic relaxation

Yoda1 类似物 (Dooku1) 可拮抗 Yoda1 引起的 Piezo1 激活和主动脉舒张

Elizabeth L Evans, Kevin Cuthbertson, Naima Endesh, Baptiste Rode, Nicola M Blythe, Adam J Hyman, Sally J Hall, Hannah J Gaunt, Melanie J Ludlow, Richard Foster, David J Beech

Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance

Piezo1 通道感知全身身体活动,以重置心血管稳态并提高体能

Baptiste Rode, Jian Shi, Naima Endesh, Mark J Drinkhill, Peter J Webster, Sabine J Lotteau, Marc A Bailey, Nadira Y Yuldasheva, Melanie J Ludlow, Richard M Cubbon, Jing Li, T Simon Futers, Lara Morley, Hannah J Gaunt, Katarzyna Marszalek, Hema Viswambharan, Kevin Cuthbertson, Paul D Baxter, Richard