日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hippocampal P2X7 and A2A purinoceptors mediate cognitive impairment caused by long-lasting epileptic seizures

海马P2X7和A2A嘌呤受体介导长期癫痫发作引起的认知障碍

Sun, Meng-Juan; Ren, Wen-Jing; Zhao, Ya-Fei; Li, Xuan; Khan, Muhammad Tahir; Cheng, Xin-Yi; Yin, Hai-Yan; Verkhratsky, Alexei; Engel, Tobias; Rubini, Patrizia; Tang, Yong; Illes, Peter

Adenosine A(2A) receptor and glial glutamate transporter GLT-1 are synergistic targets to reduce brain hyperexcitability after traumatic brain injury in mice.

腺苷 A(2A) 受体和胶质谷氨酸转运蛋白 GLT-1 是降低小鼠脑外伤后脑过度兴奋性的协同靶点

Alves Mariana, Gerbatin Rogério, Kalmeijer Rebecca, Fedele Denise, Engel Tobias, Boison Detlev

Penicillium and Talaromyces diversity in cystic fibrosis patient sample and the description of a new species, Penicillium subluteum sp. nov. (Eurotiales, Aspergillaceae)

囊性纤维化患者样本中青霉菌和塔拉霉菌的多样性及新种青霉菌(Penicillium subluteum sp. nov.)(散囊菌目,曲霉科)的描述

Zhou, Ya Bin; Meijer, Eelco F J; Engel, Tobias G P; Wang, Qi Ming; Feng, Zi Xuan; Hagen, Ferry; Meijer, Martin; Kraak, Bart; Meis, Jacques F; Houbraken, Jos

Shared and distinct microRNA profiles between HT22, N2A and SH-SY5Y cell lines and primary mouse hippocampal neurons

HT22、N2A 和 SH-SY5Y 细胞系与原代小鼠海马神经元之间共有和独特的 microRNA 谱

Murphy, Ronan; Villegas-Salmerón, Javier; Sanz-Rodriguez, Amaya; Engel, Tobias; Mooney, Catherine; Henshall, David C; Jimenez-Mateos, Eva M

The CALHM1 blocker CGP37157 increases seizure severity during status epilepticus in adult mice

CALHM1阻断剂CGP37157可加重成年小鼠癫痫持续状态期间的癫痫发作严重程度。

Mitra, Meghma; Rodriguez, Amaya Sanz; Delanty, Norman; Beausang, Alan; Brett, Francesca M; Farrell, Michael A; Cryan, Jane; O'Brien, Donncha F; Henshall, David; Cano-Abad, Maria F; Engel, Tobias

The Purinergic P2X7 Receptor as a Target for Adjunctive Treatment for Drug-Refractory Epilepsy

嘌呤能P2X7受体作为药物难治性癫痫辅助治疗的靶点

Thakku Sivakumar, Divyeshz; Jain, Krishi; Alfehaid, Noura; Wang, Yitao; Teng, Xinchen; Fischer, Wolfgang; Engel, Tobias

Distinct fingerprints of tRNA-derived small non-coding RNA in animal models of neurodegeneration

神经退行性疾病动物模型中tRNA衍生的小非编码RNA的独特指纹图谱

Baindoor, Sharada; Gibriel, Hesham A Y; Venø, Morten T; Su, Junyi; Morrissey, Elena Perez; Jirström, Elisabeth; Woods, Ina; Kenny, Aidan; Alves, Mariana; Halang, Luise; Fabbrizio, Paola; Bilen, Maria; Engel, Tobias; Hogg, Marion C; Bendotti, Caterina; Nardo, Giovanni; Slack, Ruth S; Kjems, Jørgen; Prehn, Jochen H M

P2X7 receptor inhibition ameliorates ubiquitin-proteasome system dysfunction associated with Alzheimer's disease

P2X7受体抑制可改善与阿尔茨海默病相关的泛素-蛋白酶体系统功能障碍

Bianchi, Carolina; Alvarez-Castelao, Beatriz; Sebastián-Serrano, Álvaro; Di Lauro, Caterina; Soria-Tobar, Lucia; Nicke, Annette; Engel, Tobias; Díaz-Hernández, Miguel

Increased uptake of the P2X7 receptor radiotracer (18) F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice

雄性小鼠癫痫持续状态严重程度与脑和外周器官中 P2X7 受体放射性示踪剂 (18) F-JNJ-64413739 的摄取量增加相关。

Morgan, James; Moreno, Oscar; Alves, Mariana; Baz, Zuriñe; Menéndez Méndez, Aida; Leister, Hanna; Melia, Ciara; Smith, Jonathon; Visekruna, Alexander; Nicke, Annette; Bhattacharya, Anindya; Ceusters, Marc; Henshall, David C; Gómez-Vallejo, Vanessa; Llop, Jordi; Engel, Tobias

The P2X7 Receptor as a Mechanistic Biomarker for Epilepsy

P2X7受体作为癫痫的机制性生物标志物

Engel, Tobias