Hypoxia-inducible factor 1α activates insulin-induced gene 2 (Insig-2) transcription for degradation of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase in the liver.
缺氧诱导因子 1α 激活胰岛素诱导基因 2 (Insig-2) 转录，从而降解肝脏中的 3-羟基-3-甲基戊二酰 (HMG)-CoA 还原酶
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M117.788562
Hwang Seonghwan, Nguyen Andrew D, Jo Youngah, Engelking Luke J, Brugarolas James, DeBose-Boyd Russell A
