日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human immunodeficiency virus type 1 replication in the absence of integrase-mediated dna recombination: definition of permissive and nonpermissive T-cell lines.

人类免疫缺陷病毒 1 型在缺乏整合酶介导的 DNA 重组的情况下复制:容许性和非容许性 T 细胞系的定义

Nakajima N, Lu R, Engelman A

Characterization of a replication-defective human immunodeficiency virus type 1 att site mutant that is blocked after the 3' processing step of retroviral integration

对一种复制缺陷型人类免疫缺陷病毒1型att位点突变体进行表征,该突变体在逆转录病毒整合的3'加工步骤后受阻。

Chen, H; Engelman, A

Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking

通过基于结构的分析和光交联技术鉴定HIV-1整合酶与病毒DNA之间的关键接触点

Jenkins, T M; Esposito, D; Engelman, A; Craigie, R

A mutation in integrase can compensate for mutations in the simian immunodeficiency virus att site

整合酶的突变可以补偿猿猴免疫缺陷病毒att位点的突变。

Du, Z; Ilyinskii, P O; Lally, K; Desrosiers, R C; Engelman, A

Structure-based mutagenesis of the catalytic domain of human immunodeficiency virus type 1 integrase

基于结构的人类免疫缺陷病毒1型整合酶催化结构域诱变

Engelman, A; Liu, Y; Chen, H; Farzan, M; Dyda, F

Reversion of a human immunodeficiency virus type 1 integrase mutant at a second site restores enzyme function and virus infectivity

人类免疫缺陷病毒1型整合酶突变体在第二位点的回复突变可恢复酶功能和病毒感染性。

Taddeo, B; Carlini, F; Verani, P; Engelman, A

Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication

人类免疫缺陷病毒1型整合酶突变对病毒复制的多种影响

Engelman, A; Englund, G; Orenstein, J M; Martin, M A; Craigie, R

Efficient magnesium-dependent human immunodeficiency virus type 1 integrase activity

高效的镁依赖性人类免疫缺陷病毒1型整合酶活性

Engelman, A; Craigie, R

Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex

HIV-1整合酶离散功能域的鉴定及其在活性多聚体复合物中的组织结构

Engelman, A; Bushman, F D; Craigie, R

Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro

体外鉴定对人类免疫缺陷病毒1型整合酶功能至关重要的保守氨基酸残基

Engelman, A; Craigie, R