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Efficacy of metronomic vinorelbine in elderly patients with advanced non-small-cell lung cancer and poor performance status

节拍式长春瑞滨治疗老年晚期非小细胞肺癌且体能状态较差患者的疗效

期刊:Current Oncology

影响因子:3.4

doi:10.3747/co.24.3486

Bilir, C; Durak, S; Kızılkaya, B; Hacıbekiroglu, I; Nayır, E; Engin, H

Modeling of RAS complexes supports roles in cancer for less studied partners

RAS复合物的建模支持了研究较少的受体在癌症中的作用。

期刊:BMC Biophysics

影响因子:

doi:10.1186/s13628-017-0037-6

Engin, H Billur; Carlin, Daniel; Pratt, Dexter; Carter, Hannah

Aminoglycoside binding and catalysis specificity of aminoglycoside 2″-phosphotransferase IVa: A thermodynamic, structural and kinetic study

氨基糖苷类 2″-磷酸转移酶 IVa 的氨基糖苷结合和催化特异性：热力学、结构和动力学研究

期刊:

影响因子:3.3

doi:10.1016/j.bbagen.2016.01.016

Elise Kaplan, Jean-François Guichou, Laurent Chaloin, Simone Kunzelmann, Nadia Leban, Engin H Serpersu, Corinne Lionne

信号转导

发表日期：2016

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Structure-Based Analysis Reveals Cancer Missense Mutations Target Protein Interaction Interfaces

基于结构的分析揭示癌症错义突变靶向蛋白质相互作用界面

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0152929

Engin, H Billur; Kreisberg, Jason F; Carter, Hannah

Integrating structure to protein-protein interaction networks that drive metastasis to brain and lung in breast cancer

整合结构与驱动乳腺癌脑转移和肺转移的蛋白质-蛋白质相互作用网络

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0081035

Engin, H Billur; Guney, Emre; Keskin, Ozlem; Oliva, Baldo; Gursoy, Attila

A strategy based on protein-protein interface motifs may help in identifying drug off-targets

基于蛋白质-蛋白质相互作用界面基序的策略可能有助于识别药物脱靶效应。

期刊:Journal of Chemical Information and Modeling

影响因子:5.3

doi:10.1021/ci300072q

Engin, H Billur; Keskin, Ozlem; Nussinov, Ruth; Gursoy, Attila

发表日期：2012

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Transient kinetics of aminoglycoside phosphotransferase(3')-IIIa reveals a potential drug target in the antibiotic resistance mechanism

氨基糖苷磷酸转移酶(3')-IIIa的瞬态动力学揭示了抗生素耐药机制中的潜在药物靶点。

期刊:FEBS Letters

影响因子:3

doi:10.1016/j.febslet.2012.10.027

Lallemand, Perrine; Leban, Nadia; Kunzelmann, Simone; Chaloin, Laurent; Serpersu, Engin H; Webb, Martin R; Barman, Tom; Lionne, Corinne

发表日期：2012

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"Catch and Release": A Variation of the Archetypal Nucleotidyl Transfer Reaction

“捕获与释放”：一种典型的核苷酸转移反应的变体

A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad

低势垒氢键在非典型催化三元组中介导抗生素耐药性。

Efficacy of metronomic vinorelbine in elderly patients with advanced non-small-cell lung cancer and poor performance status

节拍式长春瑞滨治疗老年晚期非小细胞肺癌且体能状态较差患者的疗效

Modeling of RAS complexes supports roles in cancer for less studied partners

RAS复合物的建模支持了研究较少的受体在癌症中的作用。

Aminoglycoside binding and catalysis specificity of aminoglycoside 2″-phosphotransferase IVa: A thermodynamic, structural and kinetic study

氨基糖苷类 2″-磷酸转移酶 IVa 的氨基糖苷结合和催化特异性：热力学、结构和动力学研究

Structure-Based Analysis Reveals Cancer Missense Mutations Target Protein Interaction Interfaces

基于结构的分析揭示癌症错义突变靶向蛋白质相互作用界面

Integrating structure to protein-protein interaction networks that drive metastasis to brain and lung in breast cancer

整合结构与驱动乳腺癌脑转移和肺转移的蛋白质-蛋白质相互作用网络

A strategy based on protein-protein interface motifs may help in identifying drug off-targets

基于蛋白质-蛋白质相互作用界面基序的策略可能有助于识别药物脱靶效应。

Transient kinetics of aminoglycoside phosphotransferase(3')-IIIa reveals a potential drug target in the antibiotic resistance mechanism

氨基糖苷磷酸转移酶(3')-IIIa的瞬态动力学揭示了抗生素耐药机制中的潜在药物靶点。