日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A Randomized Phase 1 Clinical Trial of a Respiratory Syncytial Virus and Human Metapneumovirus Combination Protein-Based Virus-like Particle Vaccine in Adults 60-75 Years of Age

一项针对60-75岁成年人的呼吸道合胞病毒和人偏肺病毒联合蛋白病毒样颗粒疫苗的随机I期临床试验

期刊:Open Forum Infectious Diseases
影响因子:3.8
doi:10.1093/ofid/ofaf160
Shapiro, Craig; Sánchez-Crespo, Nelia; Ciarlet, Max; Hourguettes, Nicholas; Wen, Judy; Rida, Wasima; Price, Jennifer; Engram, April E; Adams, Elizabeth M; Kanesa-Thasan, Niranjan
微生物学
Human
发表日期：2025
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Introduction of mismatches in a random shRNA-encoding library improves potency for phenotypic selection

在随机shRNA编码文库中引入错配可提高表型筛选的效力。

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0087390
Wang, Yongping; Speier, Jacqueline S; Engram-Pearl, Jessica; Wilson, Robert B
发表日期：2014
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Critical role of CD4 T cells in maintaining lymphoid tissue structure for immune cell homeostasis and reconstitution

CD4 T 细胞在维持淋巴组织结构以实现免疫细胞稳态和重建方面发挥着关键作用

期刊:Blood
影响因子:21
doi:10.1182/blood-2012-03-418624
Ming Zeng, Mirko Paiardini, Jessica C Engram, Greg J Beilman, Jeffrey G Chipman, Timothy W Schacker, Guido Silvestri, Ashley T Haase
细胞生物学
T细胞
发表日期：2012
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Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques

CD4⁺ T 细胞的耗竭会消除 SIV 感染的恒河猴病毒血症高峰后的下降趋势。

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI46023
Ortiz, Alexandra M; Klatt, Nichole R; Li, Bing; Yi, Yanjie; Tabb, Brian; Hao, Xing Pei; Sternberg, Lawrence; Lawson, Benton; Carnathan, Paul M; Cramer, Elizabeth M; Engram, Jessica C; Little, Dawn M; Ryzhova, Elena; Gonzalez-Scarano, Francisco; Paiardini, Mirko; Ansari, Aftab A; Ratcliffe, Sarah; Else, James G; Brenchley, Jason M; Collman, Ronald G; Estes, Jacob D; Derdeyn, Cynthia A; Silvestri, Guido
T细胞
炎症/感染
微生物学
细胞生物学
CD4
发表日期：2011
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Vaccine-induced T cells provide partial protection against high-dose rectal SIVmac239 challenge of rhesus macaques

疫苗诱导的T细胞可对恒河猴高剂量直肠SIVmac239攻击提供部分保护

期刊:Molecular Therapy
影响因子:12
doi:10.1038/mt.2010.238
Lasaro, Marcio O; Haut, Larissa H; Zhou, Xiangyang; Xiang, Zhiquan; Zhou, Dongming; Li, Yan; Giles-Davis, Wynetta; Li, Hua; Engram, Jessica C; Dimenna, Lauren J; Bian, Ang; Sazanovich, Marina; Parzych, Elizabeth M; Kurupati, Raj; Small, Juliana C; Wu, Te-Lang; Leskowitz, Rachel M; Klatt, Nicole R; Brenchley, Jason M; Garber, David A; Lewis, Mark; Ratcliffe, Sarah J; Betts, Michael R; Silvestri, Guido; Ertl, Hildegund C
细胞生物学
T细胞
T细胞
免疫/内分泌
发表日期：2011
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Viral CTL escape mutants are generated in lymph nodes and subsequently become fixed in plasma and rectal mucosa during acute SIV infection of macaques

在猕猴急性SIV感染期间，病毒CTL逃逸突变体在淋巴结中产生，随后固定在血浆和直肠黏膜中。

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1002048
Vanderford, Thomas H; Bleckwehl, Chelsea; Engram, Jessica C; Dunham, Richard M; Klatt, Nichole R; Feinberg, Mark B; Garber, David A; Betts, Michael R; Silvestri, Guido
炎症/感染
微生物学
发表日期：2011
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Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates

非人灵长类动物体内 CD4+ 和 CD8+ 淋巴细胞耗竭后谱系特异性 T 细胞重建

期刊:Blood
影响因子:23.1
doi:10.1182/blood-2010-01-263814
Engram, Jessica C; Cervasi, Barbara; Borghans, Jose A M; Klatt, Nichole R; Gordon, Shari N; Chahroudi, Ann; Else, James G; Mittler, Robert S; Sodora, Donald L; de Boer, Rob J; Brenchley, Jason M; Silvestri, Guido; Paiardini, Mirko
CD8
细胞生物学
T细胞
CD4
发表日期：2010
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Bone marrow-based homeostatic proliferation of mature T cells in nonhuman primates: implications for AIDS pathogenesis

非人灵长类动物骨髓中成熟T细胞的稳态增殖：对艾滋病发病机制的启示

期刊:Blood
影响因子:23.1
doi:10.1182/blood-2008-06-159442
Paiardini, Mirko; Cervasi, Barbara; Engram, Jessica C; Gordon, Shari N; Klatt, Nichole R; Muthukumar, Alagarraju; Else, James; Mittler, Robert S; Staprans, Silvija I; Sodora, Donald L; Silvestri, Guido
细胞生物学
T细胞
T细胞
免疫/内分泌
发表日期：2009
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Adenovirus vector-induced immune responses in nonhuman primates: responses to prime boost regimens

腺病毒载体诱导的非人灵长类动物免疫反应：对初免加强免疫方案的反应

期刊:Journal of Immunology
影响因子:3.4
doi:10.4049/jimmunol.0900317
Tatsis, Nia; Lasaro, Marcio O; Lin, Shih-Wen; Haut, Larissa H; Xiang, Zhi Q; Zhou, Dongming; Dimenna, Lauren; Li, Hua; Bian, Ang; Abdulla, Sarah; Li, Yan; Giles-Davis, Wynetta; Engram, Jessica; Ratcliffe, Sarah J; Silvestri, Guido; Ertl, Hildegund C; Betts, Michael R
微生物学
免疫/内分泌
发表日期：2009
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Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys

活化 CD4+ T 细胞的可用性决定了自然感染 SIV 的白眉猴的病毒血症水平

期刊:Journal of Clinical Investigation
影响因子:13.3
doi:10.1172/JCI33814
Nichole R Klatt, Francois Villinger, Pavel Bostik, Shari N Gordon, Lara Pereira, Jessica C Engram, Ann Mayne, Richard M Dunham, Benton Lawson, Sarah J Ratcliffe, Donald L Sodora, James Else, Keith Reimann, Silvija I Staprans, Ashley T Haase, Jacob D Estes, Guido Silvestri, Aftab A Ansari
微生物学
细胞生物学
T细胞
发表日期：2008
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