日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Treatment with the CCR5 antagonist OB-002 reduces lung pathology, but does not prevent disease in a Syrian hamster model of SARS-CoV-2 infection

在SARS-CoV-2感染的叙利亚仓鼠模型中，使用CCR5拮抗剂OB-002治疗可减轻肺部病理，但不能预防疾病。

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0316952
Warner, Bryce M; Vendramelli, Robert; Boese, Amrit S; Audet, Jonathan; Tailor, Nikesh; Meilleur, Courtney; Glowach, Nathan; Willman, Marnie; Truong, Thang; Moffat, Estella; Tierney, Kevin; Kosak, Beata; Dhanidina, Irfan; Engstrom, Jarret; Korczak, Bozena; McGowan, Ian; Embury-Hyatt, Carissa; Kobasa, Darwyn
炎症/感染
CCR5
SARS-CoV-2
发表日期：2025
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A Randomized, Open-Label, Crossover Phase 1 Safety and Pharmacokinetic Study of Oral Maraviroc and Maraviroc 1% Gel (the CHARM-03 Study)

一项随机、开放标签、交叉的 1 期口服马拉维罗和 1% 马拉维罗凝胶安全性和药代动力学研究（CHARM-03 研究）

期刊:Aids Research and Human Retroviruses
影响因子:1.1
doi:10.1089/AID.2021.0096
McGowan, Ian M; Chawki, Sylvain; Hendrix, Craig W; Anton, Peter A; Marzinke, Mark A; Brand, Rhonda M; Engstrom, Jarret C; Rohan, Lisa C; Abebe, Kaleab Z; Richardson-Harman, Nicola; Siegel, Aaron; Reinhart, Alex; Steytler, John; Stall, Ronald; Spiegel, Hans; Chen, Beatrice; Achilles, Sharon L; Jacobson, Cindy E; Khanukova, Elena; Cranston, Ross D
发表日期：2022
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Tofacitinib inhibits inflammatory cytokines from ulcerative colitis and healthy mucosal explants and is associated with pSTAT1/3 reduction in T-cells

托法替尼可抑制溃疡性结肠炎和健康黏膜外植体中的炎症细胞因子，并与T细胞中pSTAT1/3的减少有关。

期刊:American Journal of Physiology-Gastrointestinal and Liver Physiology
影响因子:3.3
doi:10.1152/ajpgi.00383.2020
Brand, Rhonda M; Moore, Beverley A; Zyhowski, Ashley; Siegel, Aaron; Uttam, Shikhar; Metter, E Jeffrey; Engstrom, Jarret; Brand, Randall E; Biswas, Nabanita; Whitcomb, David C; Binion, David G; Schwartz, Marc; McGowan, Ian
STAT1
肠炎
T细胞
炎症
炎症/感染
JAK/STAT
T细胞
细胞生物学
结肠炎
免疫/内分泌
发表日期：2021
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The Use of Droplet Digital PCR to Quantify HIV-1 Replication in the Colorectal Explant Model.

利用液滴数字PCR定量分析结直肠外植体模型中的HIV-1复制

期刊:Aids Research and Human Retroviruses
影响因子:1.1
doi:10.1089/AID.2018.0227
Myerski Ashley, Siegel Aaron, Engstrom Jarret, McGowan Ian, Brand Rhonda M
HIV
微生物学
发表日期：2019
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Project Gel a Randomized Rectal Microbicide Safety and Acceptability Study in Young Men and Transgender Women

Project Gel：一项针对年轻男性和跨性别女性的随机直肠杀微生物剂安全性和接受度研究

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0158310
McGowan, Ian; Cranston, Ross D; Mayer, Kenneth H; Febo, Irma; Duffill, Kathryn; Siegel, Aaron; Engstrom, Jarret C; Nikiforov, Alexyi; Park, Seo-Young; Brand, Rhonda M; Jacobson, Cindy; Giguere, Rebecca; Dolezal, Curtis; Frasca, Timothy; Leu, Cheng-Shiun; Schwartz, Jill L; Carballo-Diéguez, Alex
微生物学
发表日期：2016
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A Phase 1 Randomized, Open Label, Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Three Formulations of Tenofovir 1% Gel (the CHARM-01 Study)

一项针对三种 1% 替诺福韦凝胶制剂的 1 期随机、开放标签、直肠安全性、可接受性、药代动力学和药效学研究（CHARM-01 研究）

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0125363
Mcgowan, Ian; Cranston, Ross D; Duffill, Kathryn; Siegel, Aaron; Engstrom, Jarret C; Nikiforov, Alexyi; Jacobson, Cindy; Rehman, Khaja K; Elliott, Julie; Khanukhova, Elena; Abebe, Kaleab; Mauck, Christine; Spiegel, Hans M L; Dezzutti, Charlene S; Rohan, Lisa C; Marzinke, Mark A; Hiruy, Hiwot; Hendrix, Craig W; Richardson-Harman, Nicola; Anton, Peter A
发表日期：2015
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