日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation

微生物群通过调控T细胞克隆选择来增强干细胞移植后的移植物抗宿主病。

Albert C Yeh ,Motoko Koyama ,Olivia G Waltner ,Simone A Minnie ,Julie R Boiko ,Tamer B Shabaneh ,Shuichiro Takahashi ,Ping Zhang ,Kathleen S Ensbey ,Christine R Schmidt ,Samuel R W Legg ,Tomoko Sekiguchi ,Ethan Nelson ,Shruti S Bhise ,Andrew R Stevens ,Tracy Goodpaster ,Saranya Chakka ,Scott N Furlan ,Kate A Markey ,Marie E Bleakley ,Charles O Elson ,Philip H Bradley ,Geoffrey R Hill

Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation

在自体干细胞动员和移植过程中,调节性T细胞抑制骨髓瘤特异性免疫反应。

Takahashi, Shuichiro; Minnie, Simone A; Ensbey, Kathleen S; Schmidt, Christine R; Sekiguchi, Tomoko; Legg, Samuel R W; Zhang, Ping; Koyama, Motoko; Olver, Stuart D; Collinge, Alika D; Keshmiri, Sara; Comstock, Melissa L; Varelias, Antiopi; Green, Damian J; Hill, Geoffrey R

TIM-3+ CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies

具有终末衰竭表型的 TIM-3+ CD8 T 细胞在血液系统恶性肿瘤中保留功能能力

Simone A Minnie, Olivia G Waltner, Ping Zhang, Shuichiro Takahashi, Nicole S Nemychenkov, Kathleen S Ensbey, Christine R Schmidt, Samuel R W Legg, Melissa Comstock, Julie R Boiko, Ethan Nelson, Shruti S Bhise, Alec B Wilkens, Motoko Koyama, Madhav V Dhodapkar, Marta Chesi, Stanley R Riddell, Damian

IL-6-mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation

IL-6 介导的内皮损伤削弱骨髓移植后的抗病毒体液免疫

Ping Zhang, Peter Fleming, Christopher E Andoniou, Olivia G Waltner, Shruti S Bhise, Jose Paulo Martins, Benjamin A McEnroe, Valentina Voigt, Sheridan Daly, Rachel D Kuns, Adaeze P Ekwe, Andrea S Henden, Alda Saldan, Stuart Olver, Antiopi Varelias, Corey Smith, Christine R Schmidt, Kathleen S Ensbey

Intestinal microbiota controls graft-versus-host disease independent of donor-host genetic disparity

肠道菌群控制移植物抗宿主病,且与供体-宿主遗传差异无关。

Motoko Koyama ,Daniel S Hippe ,Sujatha Srinivasan ,Sean C Proll ,Oriana Miltiadous ,Naisi Li ,Ping Zhang ,Kathleen S Ensbey ,Noah G Hoffman ,Christine R Schmidt ,Albert C Yeh ,Simone A Minnie ,Susan M Strenk ,Tina L Fiedler ,Namita Hattangady ,Jacob Kowalsky ,Willian M Grady ,Mariapia A Degli-Esposti ,Antiopi Varelias ,Andrew D Clouston ,Marcel R M van den Brink ,Neelendu Dey ,Timothy W Randolph ,Kate A Markey ,David N Fredricks ,Geoffrey R Hill

TIGIT inhibition and lenalidomide synergistically promote antimyeloma immune responses after stem cell transplantation in mice

TIGIT 抑制剂和来那度胺协同促进小鼠干细胞移植后的抗骨髓瘤免疫反应

Simone A Minnie, Olivia G Waltner, Kathleen S Ensbey, Stuart D Olver, Alika D Collinge, David P Sester, Christine R Schmidt, Samuel Rw Legg, Shuichiro Takahashi, Nicole S Nemychenkov, Tomoko Sekiguchi, Gregory Driessens, Ping Zhang, Motoko Koyama, Andrew Spencer, Leona A Holmberg, Scott N Furlan, An

Activation of the zinc-sensing receptor GPR39 promotes T-cell reconstitution after hematopoietic cell transplant in mice

锌敏感受体 GPR39 的激活促进小鼠造血细胞移植后的 T 细胞重建

Lorenzo Iovino, Kirsten Cooper, Paul deRoos, Sinéad Kinsella, Cindy Evandy, Tamas Ugrai, Francesco Mazziotta, Kathleen S Ensbey, David Granadier, Kayla Hopwo, Colton Smith, Alex Gagnon, Sara Galimberti, Mario Petrini, Geoffrey R Hill, Jarrod A Dudakov

Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity

耗尽同种反应性 T 细胞后,可以靶向干细胞样记忆 T 细胞来产生肿瘤特异性免疫

Simone A Minnie, Olivia G Waltner, Kathleen S Ensbey, Nicole S Nemychenkov, Christine R Schmidt, Shruti S Bhise, Samuel R W Legg, Gabriela Campoy, Luke D Samson, Rachel D Kuns, Ting Zhou, John D Huck, Slavica Vuckovic, Danniel Zamora, Albert Yeh, Andrew Spencer, Motoko Koyama, Kate A Markey, Steven

CMV exposure drives long-term CD57+ CD4 memory T-cell inflation following allogeneic stem cell transplant

巨细胞病毒暴露可导致异基因造血干细胞移植后CD57+CD4记忆T细胞长期增殖。

Yeh, Albert C; Varelias, Antiopi; Reddy, Anupama; Barone, Sierra M; Olver, Stuart D; Chilson, Kate; Onstad, Lynn E; Ensbey, Kathleen S; Henden, Andrea S; Samson, Luke; Jaeger, Carla A; Bi, Timothy; Dahlman, Kimberly B; Kim, Tae Kon; Zhang, Ping; Degli-Esposti, Mariapia A; Newell, Evan W; Jagasia, Madan H; Irish, Jonathan M; Lee, Stephanie J; Hill, Geoffrey R

Peritransplant glucocorticoids redistribute donor T cells to the bone marrow and prevent relapse after haploidentical SCT

移植前后使用糖皮质激素可将供体T细胞重新分配至骨髓,并预防单倍体相合造血干细胞移植后的复发。

Takayuki Inoue,Motoko Koyama,Katsuji Kaida,Kazuhiro Ikegame,Kathleen S Ensbey,Luke Samson,Shuichiro Takahashi,Ping Zhang,Simone A Minnie,Satoshi Maruyama,Shinichi Ishii,Takashi Daimon,Takahiro Fukuda,Hirohisa Nakamae,Takahide Ara,Yumiko Maruyama,Ken Ishiyama,Tatsuo Ichinohe,Yoshiko Atsuta,Bruce R Blazar,Scott N Furlan,Hiroyasu Ogawa,Geoffrey R Hill