日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Transcription Factor Engineering in Aspergillus nidulans Leads to the Discovery of an Orsellinaldehyde Derivative Produced via an Unlinked Polyketide Synthase Gene

通过对构巢曲霉进行转录因子工程改造，发现了一种通过非连接聚酮合酶基因产生的奥尔塞林醛衍生物。

期刊:Journal of Natural Products
影响因子:3.6
doi:10.1021/acs.jnatprod.4c00483
Rabot, Chris; Grau, Michelle F; Entwistle, Ruth; Chiang, Yi-Ming; Zamora de Roberts, Yamilex; Ahuja, Manmeet; Oakley, C Elizabeth; Wang, Clay C C; Todd, Richard B; Oakley, Berl R
发表日期：2024
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Overexpression of an LaeA-like Methyltransferase Upregulates Secondary Metabolite Production in Aspergillus nidulans

LaeA样甲基转移酶的过表达上调构巢曲霉的次级代谢产物生成

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.9b00380
Grau, Michelle F; Entwistle, Ruth; Oakley, C Elizabeth; Wang, Clay C C; Oakley, Berl R
代谢
发表日期：2019
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Hybrid Transcription Factor Engineering Activates the Silent Secondary Metabolite Gene Cluster for (+)-Asperlin in Aspergillus nidulans

杂交转录因子工程激活构巢曲霉中沉默的次级代谢产物基因簇（+）-Asperlin

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.8b00679
Grau, Michelle F; Entwistle, Ruth; Chiang, Yi-Ming; Ahuja, Manmeet; Oakley, C Elizabeth; Akashi, Tomohiro; Wang, Clay C C; Todd, Richard B; Oakley, Berl R
代谢
发表日期：2018
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Discovery of McrA, a master regulator of Aspergillus secondary metabolism.

发现了 McrA，它是曲霉次级代谢的主要调控因子

期刊:Molecular Microbiology
影响因子:2.6
doi:10.1111/mmi.13562
Oakley C Elizabeth, Ahuja Manmeet, Sun Wei-Wen, Entwistle Ruth, Akashi Tomohiro, Yaegashi Junko, Guo Chun-Jun, Cerqueira Gustavo C, Russo Wortman Jennifer, Wang Clay C C, Chiang Yi-Ming, Oakley Berl R
代谢
发表日期：2017
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Overexpression of a three-gene conidial pigment biosynthetic pathway in Aspergillus nidulans reveals the first NRPS known to acetylate tryptophan

在构巢曲霉中过表达三基因分生孢子色素生物合成途径，揭示了首个已知能乙酰化色氨酸的非核糖体肽合成酶（NRPS）。

期刊:Fungal Genetics and Biology
影响因子:2.3
doi:10.1016/j.fgb.2017.01.006
Sung, Calvin T; Chang, Shu-Lin; Entwistle, Ruth; Ahn, Green; Lin, Tzu-Shyang; Petrova, Vessela; Yeh, Hsu-Hua; Praseuth, Mike B; Chiang, Yi-Ming; Oakley, Berl R; Wang, Clay C C
乙酰化
表观遗传
发表日期：2017
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Development of Genetic Dereplication Strains in Aspergillus nidulans Results in the Discovery of Aspercryptin

构巢曲霉基因去重复菌株的构建导致曲霉隐曲霉素的发现

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.201507097
Chiang, Yi-Ming; Ahuja, Manmeet; Oakley, C Elizabeth; Entwistle, Ruth; Asokan, Anabanadam; Zutz, Christoph; Wang, Clay C C; Oakley, Berl R
发表日期：2016
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Inhibition of Tau aggregation by three Aspergillus nidulans secondary metabolites: 2,ω-dihydroxyemodin, asperthecin, and asperbenzaldehyde

三种构巢曲霉次级代谢产物（2,ω-二羟基大黄素、曲霉素和曲霉苯甲醛）对Tau蛋白聚集的抑制作用

期刊:Planta Medica
影响因子:2
doi:10.1055/s-0033-1360180
Paranjape, Smita R; Chiang, Yi-Ming; Sanchez, James F; Entwistle, Ruth; Wang, Clay C C; Oakley, Berl R; Gamblin, T Chris
代谢
发表日期：2014
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Molecular genetic characterization of the biosynthesis cluster of a prenylated isoindolinone alkaloid aspernidine A in Aspergillus nidulans

构巢曲霉中异吲哚啉酮生物碱阿斯帕尼定A生物合成簇的分子遗传学特征

期刊:Organic Letters
影响因子:5
doi:10.1021/ol401187b
Yaegashi, Junko; Praseuth, Mike B; Tyan, Shiaw-Wei; Sanchez, James F; Entwistle, Ruth; Chiang, Yi-Ming; Oakley, Berl R; Wang, Clay C C
发表日期：2013
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Differentiating between models of epothilone binding to microtubules using tubulin mutagenesis, cytotoxicity, and molecular modeling

利用微管蛋白诱变、细胞毒性和分子建模来区分埃博霉素与微管结合的不同模型

期刊:ChemMedChem
影响因子:3.4
doi:10.1002/cmdc.201200286
Entwistle, Ruth A; Rizk, Rania S; Cheng, Daniel M; Lushington, Gerald H; Himes, Richard H; Gupta, Mohan L Jr
细胞生物学
毒理研究
发表日期：2012
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Identification and molecular genetic analysis of the cichorine gene cluster in Aspergillus nidulans

构巢曲霉中菊粉基因簇的鉴定和分子遗传分析

期刊:Medchemcomm
影响因子:
doi:10.1039/C2MD20055D
Sanchez, James F; Entwistle, Ruth; Corcoran, David; Oakley, Berl R; Wang, Clay C C
发表日期：2012
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