日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genome-wide analysis implicates inner ear development in Ménière's disease

全基因组分析表明内耳发育与梅尼埃病有关

Shi, Zhuozheng; Mandla, Ravi; Li, Jingjing; Li, Xinzhe; Zhang, Zixuan Eleanor; Chen, Sixing; Lapinska, Sandra; Flynn-Carroll, Alexander O; Pasaniuc, Bogdan; Epstein, Douglas J; Mathieson, Iain

Impaired pain in mice lacking first-order posterior medial thalamic neurons.

缺乏一级后内侧丘脑神经元的小鼠出现痛觉障碍

Sgourdou Paraskevi, Schaffler Melanie, Choi Kyuhyun, McCall Nora M, Burdge Justin, Williams Joelle, Corder Gregory, Fuccillo Marc V, Abdus-Saboor Ishmail, Epstein Douglas J

Limited Utility of Existing Hearing Loss Panels in the Assessment of Early-Onset, Bilateral Meniere's Disease

现有听力损失专家组在评估早发性双侧梅尼埃病方面的作用有限

Shah, Keshav V; Jung, Christian; Talian, Daniel; Davis, Sherrie; Epstein, Douglas J; Ruckenstein, Michael J; Hwa, Tiffany P

Multiple allelic configurations govern long-range Shh enhancer-promoter communication in the embryonic forebrain.

多种等位基因配置控制着胚胎前脑中 Shh 增强子-启动子之间的长程通讯

Harke Jailynn, Lee Jeewon R, Nguyen Son C, Arab Arian, Rakowiecki Staci M, Hugelier Siewert, Paliou Christina, Rauseo Antonella, Yunker Rebecca, Xu Kellen, Yao Yao, Lakadamyali Melike, Andrey Guillaume, Epstein Douglas J, Joyce Eric F

Gene burden analysis identifies genes associated with increased risk and severity of adult-onset hearing loss in a diverse hospital-based cohort

基因负荷分析在一项基于医院的多元化队列研究中,识别出与成人期听力损失风险增加和严重程度相关的基因。

Hui, Daniel; Mehrabi, Shadi; Quimby, Alexandra E; Chen, Tingfang; Chen, Sixing; Park, Joseph; Li, Binglan; Ruckenstein, Michael J; Rader, Daniel J; Ritchie, Marylyn D; Brant, Jason A; Epstein, Douglas J; Mathieson, Iain

Single-cell transcriptomic analysis of adult mouse pituitary reveals sexual dimorphism and physiologic demand-induced cellular plasticity

对成年小鼠垂体的单细胞转录组分析揭示了性别二态性和生理需求诱导的细胞可塑性

Ho, Yugong; Hu, Peng; Peel, Michael T; Chen, Sixing; Camara, Pablo G; Epstein, Douglas J; Wu, Hao; Liebhaber, Stephen A

Prenatal ethanol exposure in mice phenocopies Cdon mutation by impeding Shh function in the etiology of optic nerve hypoplasia

小鼠产前乙醇暴露通过阻碍Shh功能,模拟Cdon突变导致的视神经发育不全的表型。

Kahn, Benjamin M; Corman, Tanya S; Lovelace, Korah; Hong, Mingi; Krauss, Robert S; Epstein, Douglas J

Inhibition of Sox2-dependent activation of Shh in the ventral diencephalon by Tbx3 is required for formation of the neurohypophysis

Tbx3抑制腹侧间脑中Sox2依赖的Shh激活是神经垂体形成所必需的。

Trowe, Mark-Oliver; Zhao, Li; Weiss, Anna-Carina; Christoffels, Vincent; Epstein, Douglas J; Kispert, Andreas

Disruption of SoxB1-dependent Sonic hedgehog expression in the hypothalamus causes septo-optic dysplasia.

下丘脑中 SoxB1 依赖的 Sonic hedgehog 表达紊乱会导致视隔发育不良

Zhao Li, Zevallos Solsire E, Rizzoti Karine, Jeong Yongsu, Lovell-Badge Robin, Epstein Douglas J

Otic ablation of smoothened reveals direct and indirect requirements for Hedgehog signaling in inner ear development

耳蜗平滑化切除术揭示了 Hedgehog 信号通路在内耳发育中的直接和间接作用

Brown, Alexander S; Epstein, Douglas J