日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Spatial transcriptomic clocks reveal cell proximity effects in brain ageing

空间转录组时钟揭示大脑衰老中的细胞邻近效应

Eric D Sun, Olivia Y Zhou, Max Hauptschein, Nimrod Rappoport, Lucy Xu, Paloma Navarro Negredo, Ling Liu, Thomas A Rando, James Zou #, Anne Brunet #4

CRISPR-Cas9 screens reveal regulators of ageing in neural stem cells

CRISPR-Cas9筛选揭示神经干细胞衰老调控因子

Tyson J Ruetz ,Angela N Pogson # ,Chloe M Kashiwagi # ,Stephanie D Gagnon ,Bhek Morton ,Eric D Sun ,Jeeyoon Na ,Robin W Yeo ,Dena S Leeman ,David W Morgens ,C Kimberly Tsui ,Amy Li ,Michael C Bassik ,Anne Brunet

Restoration of neuronal progenitors by partial reprogramming in the aged neurogenic niche

通过对衰老神经发生微环境中的神经元祖细胞进行部分重编程来恢复其功能。

Lucy Xu ,Julliana Ramirez-Matias ,Max Hauptschein ,Eric D Sun ,Judith C Lunger ,Matthew T Buckley ,Anne Brunet

Spatiotemporal transcriptomic profiling and modeling of mouse brain at single-cell resolution reveals cell proximity effects of aging and rejuvenation

单细胞分辨率的小鼠大脑时空转录组分析和建模揭示了衰老和复原的细胞邻近效应

Eric D Sun, Olivia Y Zhou, Max Hauptschein, Nimrod Rappoport, Lucy Xu, Paloma Navarro Negredo, Ling Liu, Thomas A Rando, James Zou, Anne Brunet

Chromatin accessibility dynamics of neurogenic niche cells reveal defects in neural stem cell adhesion and migration during aging

神经发生微环境细胞染色质可及性动态变化揭示了衰老过程中神经干细胞黏附和迁移的缺陷

Robin W Yeo # ,Olivia Y Zhou # ,Brian L Zhong ,Eric D Sun ,Paloma Navarro Negredo ,Surag Nair ,Mahfuza Sharmin ,Tyson J Ruetz ,Mikaela Wilson ,Anshul Kundaje ,Alexander R Dunn ,Anne Brunet

Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain

利用细胞类型特异性衰老时钟量化大脑神经发生区域的衰老和再生

Matthew T Buckley # ,Eric D Sun # ,Benson M George ,Ling Liu ,Nicholas Schaum ,Lucy Xu ,Jaime M Reyes ,Margaret A Goodell ,Irving L Weissman ,Tony Wyss-Coray ,Thomas A Rando ,Anne Brunet

Stereotactic Ablative Radiation Therapy is Highly Safe and Effective for Elderly Patients With Early-stage Non-Small Cell Lung Cancer

立体定向消融放射疗法对早期非小细胞肺癌老年患者非常安全有效

Brooks, Eric D; Sun, Bing; Zhao, Lina; Komaki, Ritsuko; Liao, Zhonxing; Jeter, Melenda; Welsh, James W; O'Reilly, Michael S; Gomez, Daniel R; Hahn, Stephen M; Heymach, John V; Rice, David C; Chang, Joe Y

Gemcitabine metabolic pathway genetic polymorphisms and response in patients with non-small cell lung cancer

吉西他滨代谢途径基因多态性与非小细胞肺癌患者的疗效

Li, Liang; Schaid, Daniel J; Fridley, Brooke L; Kalari, Krishna R; Jenkins, Gregory D; Abo, Ryan P; Batzler, Anthony; Moon, Irene; Pelleymounter, Linda; Eckloff, Bruce W; Wieben, Eric D; Sun, Zhifu; Yang, Ping; Wang, Liewei