JAK2V617F homozygosity arises commonly and recurrently in PV and ET, but PV is characterized by expansion of a dominant homozygous subclone
JAK2V617F 纯合性在 PV 和 ET 中常见且反复出现,但 PV 的特征是显性纯合亚克隆的扩增
期刊:Blood
影响因子:21
doi:10.1182/blood-2012-05-431791
Anna L Godfrey, Edwin Chen, Francesca Pagano, Christina A Ortmann, Yvonne Silber, Beatriz Bellosillo, Paola Guglielmelli, Claire N Harrison, John T Reilly, Frank Stegelmann, Fontanet Bijou, Eric Lippert, Mary F McMullin, Jean-Michel Boiron, Konstanze Döhner, Alessandro M Vannucchi, Carlos Besses, Pe