日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model

通过 CRISPR-Cas9 工程化人类器官型皮肤模型解剖人类上皮细胞中聚糖的基本功能

Sally Dabelsteen, Emil M H Pallesen, Irina N Marinova, Mathias I Nielsen, Maria Adamopoulou, Troels B Rømer, Asha Levann, Mikkel M Andersen, Zilu Ye, David Thein, Eric P Bennett, Christian Büll, Sam J Moons, Thomas Boltje, Henrik Clausen, Sergey Y Vakhrushev, Ieva Bagdonaite, Hans H Wandall

O-glycan initiation directs distinct biological pathways and controls epithelial differentiation

O-聚糖起始指导不同的生物途径并控制上皮分化

Ieva Bagdonaite, Emil Mh Pallesen, Zilu Ye, Sergey Y Vakhrushev, Irina N Marinova, Mathias I Nielsen, Signe H Kramer, Stine F Pedersen, Hiren J Joshi, Eric P Bennett, Sally Dabelsteen, Hans H Wandall

Exploring Regulation of Protein O-Glycosylation in Isogenic Human HEK293 Cells by Differential O-Glycoproteomics

通过差异O-糖蛋白质组学探索同源人HEK293细胞中蛋白质O-糖基化的调控

Yoshiki Narimatsu, Hiren J Joshi, Katrine T Schjoldager, John Hintze, Adnan Halim, Catharina Steentoft, Rebecca Nason, Ulla Mandel, Eric P Bennett, Henrik Clausen, Sergey Y Vakhrushev

De novo expression of human polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) in colon adenocarcinoma inhibits the differentiation of colonic epithelium

人类多肽N-乙酰半乳糖胺基转移酶6(GalNAc-T6)在结肠腺癌中的从头表达抑制结肠上皮的分化

Kirstine Lavrsen, Sally Dabelsteen, Sergey Y Vakhrushev, Asha M R Levann, Amalie Dahl Haue, August Dylander, Ulla Mandel, Lars Hansen, Morten Frödin, Eric P Bennett, Hans H Wandall

Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines

通过在同源细胞系中诱导表达,探究单个多肽 GalNAc 转移酶亚型对 O-糖蛋白组的贡献

John Hintze,Zilu Ye,Yoshiki Narimatsu,Thomas Daugbjerg Madsen,Hiren J Joshi,Christoffer K Goth,Adam Linstedt,Collin Bachert,Ulla Mandel,Eric P Bennett,Sergey Y Vakhrushev,Katrine T Schjoldager

Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis

使用 FACS 富集表达核酸酶的细胞并通过扩增子分析检测插入/缺失来进行基因组编辑

Lindsey A Lonowski, Yoshiki Narimatsu, Anjum Riaz, Catherine E Delay, Zhang Yang, Francesco Niola, Katarzyna Duda, Elke A Ober, Henrik Clausen, Hans H Wandall, Steen H Hansen, Eric P Bennett, Morten Frödin

Extrinsic Functions of Lectin Domains in O-N-Acetylgalactosamine Glycan Biosynthesis

凝集素结构域在 ON-乙酰半乳糖胺聚糖生物合成中的外在功能

Virginia Lorenz, Yanina Ditamo, Romina B Cejas, Maria E Carrizo, Eric P Bennett, Henrik Clausen, Gustavo A Nores, Fernando J Irazoqui

Fast and sensitive detection of indels induced by precise gene targeting

快速灵敏地检测精准基因靶向引起的插入/缺失

Zhang Yang, Catharina Steentoft, Camilla Hauge, Lars Hansen, Allan Lind Thomsen, Francesco Niola, Malene B Vester-Christensen, Morten Frödin, Henrik Clausen, Hans H Wandall, Eric P Bennett

O-linked glycosylation of the mucin domain of the herpes simplex virus type 1-specific glycoprotein gC-1 is temporally regulated in a seed-and-spread manner

单纯疱疹病毒 1 型特异性糖蛋白 gC-1 的粘蛋白结构域的 O 连接糖基化以种子扩散的方式进行时间调控

Rickard Nordén, Adnan Halim, Kristina Nyström, Eric P Bennett, Ulla Mandel, Sigvard Olofsson, Jonas Nilsson, Göran Larson

High-efficiency genome editing via 2A-coupled co-expression of fluorescent proteins and zinc finger nucleases or CRISPR/Cas9 nickase pairs

通过 2A 偶联荧光蛋白和锌指核酸酶或 CRISPR/Cas9 切口酶对共表达实现高效基因组编辑

Katarzyna Duda, Lindsey A Lonowski, Michael Kofoed-Nielsen, Adriana Ibarra, Catherine M Delay, Qiaohua Kang, Zhang Yang, Shondra M Pruett-Miller, Eric P Bennett, Hans H Wandall, Gregory D Davis, Steen H Hansen, Morten Frödin