日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Defined TLR3 Agonist, Nexavant, Exhibits Anti-Cancer Efficacy and Potentiates Anti-PD-1 Antibody Therapy by Enhancing Immune Cell Infiltration

明确的 TLR3 激动剂 Nexavant 具有抗癌功效,并通过增强免疫细胞浸润增强抗 PD-1 抗体疗法

Seung-Hwan Lee, Young-Ho Choi, Soon Myung Kang, Min-Gyu Lee, Arnaud Debin, Eric Perouzel, Seung-Beom Hong, Dong-Ho Kim

Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells

人NLRP1是肺上皮细胞中致病性冠状病毒3CL蛋白酶的传感器

Rémi Planès,Miriam Pinilla,Karin Santoni,Audrey Hessel,Charlotte Passemar,Kenneth Lay,Perrine Paillette,Ana-Luiza Chaves Valadão,Kim Samirah Robinson,Paul Bastard,Nathaniel Lam,Ricardo Fadrique,Ida Rossi,David Pericat,Salimata Bagayoko,Stephen Adonai Leon-Icaza,Yoann Rombouts,Eric Perouzel,Michèle Tiraby

New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses

新型嵌合 TLR7/NOD2 激动剂是诱导粘膜免疫反应的有效佐剂

Alice Gutjahr, Laura Papagno, Fabienne Vernejoul, Thierry Lioux, Fabienne Jospin, Blandine Chanut, Eric Perouzel, Nicolas Rochereau, Victor Appay, Bernard Verrier, Stéphane Paul

The STING ligand cGAMP potentiates the efficacy of vaccine-induced CD8+ T cells

STING配体cGAMP可增强疫苗诱导的CD8+ T细胞的效力

Alice Gutjahr ,Laura Papagno ,Francesco Nicoli ,Tomohiro Kanuma ,Nozomi Kuse ,Mariela Pires Cabral-Piccin ,Nicolas Rochereau ,Emma Gostick ,Thierry Lioux ,Eric Perouzel ,David A Price ,Masafumi Takiguchi ,Bernard Verrier ,Takuya Yamamoto ,Stéphane Paul ,Victor Appay

STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice

STING 激动剂可促进人体细胞之间的抗病毒串扰,并为小鼠提供针对生殖器疱疹的保护

Morten K Skouboe, Alice Knudsen, Line S Reinert, Cedric Boularan, Thierry Lioux, Eric Perouzel, Martin K Thomsen, Søren R Paludan

Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses

前沿:双 TLR2 和 TLR7 配体诱导高效体液和细胞介导免疫反应

Alice Gutjahr, Laura Papagno, Francesco Nicoli, Alain Lamoureux, Fabienne Vernejoul, Thierry Lioux, Emma Gostick, David A Price, Gérard Tiraby, Eric Perouzel, Victor Appay, Bernard Verrier, Stéphane Paul