日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML

全球 miR-130a 靶基因组的鉴定揭示了 TBL1XR1 在造血干细胞自我更新和 t(8;21) AML 中的作用

Gabriela Krivdova ,Veronique Voisin ,Erwin M Schoof ,Sajid A Marhon ,Alex Murison ,Jessica L McLeod ,Martino M Gabra ,Andy G X Zeng ,Stefan Aigner ,Brian A Yee ,Alexander A Shishkin ,Eric L Van Nostrand ,Karin G Hermans ,Aaron C Trotman-Grant ,Nathan Mbong ,James A Kennedy ,Olga I Gan ,Elvin Wagenblast ,Daniel D De Carvalho ,Leonardo Salmena ,Mark D Minden ,Gary D Bader ,Gene W Yeo ,John E Dick ,Eric R Lechman

Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis

烟酰胺磷酸核糖基转移酶抑制剂通过破坏脂质稳态选择性诱导 AML 干细胞凋亡

Amit Subedi, Qiang Liu, Dhanoop M Ayyathan, David Sharon, Severine Cathelin, Mohsen Hosseini, Changjiang Xu, Veronique Voisin, Gary D Bader, Angelo D'Alessandro, Eric R Lechman, John E Dick, Mark D Minden, Jean C Y Wang, Steven M Chan

Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells

单个经 CRISPR/Cas9 编辑的人类长期造血干细胞的功能分析

Elvin Wagenblast ,Maria Azkanaz ,Sabrina A Smith ,Lorien Shakib ,Jessica L McLeod ,Gabriela Krivdova ,Joana Araújo ,Leonard D Shultz ,Olga I Gan ,John E Dick ,Eric R Lechman

An ERG Enhancer-Based Reporter Identifies Leukemia Cells with Elevated Leukemogenic Potential Driven by ERG-USP9X Feed-Forward Regulation

基于 ERG 增强子的报告基因可识别由 ERG-USP9X 前馈调节驱动的具有高致白血病潜能的白血病细胞

Nasma Aqaqe #, Muhammad Yassin #, Abed Alkader Yassin, Nour Ershaid, Chen Katz-Even, Adi Zipin-Roitman, Eitan Kugler, Eric R Lechman, Olga I Gan, Amanda Mitchell, John E Dick, Shai Izraeli, Michael Milyavsky

Attenuation of miR-126 activity expands HSC in vivo without exhaustion

miR-126 活性的减弱会导致体内 HSC 扩增但不衰竭

Eric R Lechman, Bernhard Gentner, Peter van Galen, Alice Giustacchini, Massimo Saini, Francesco E Boccalatte, Hidefumi Hiramatsu, Umberto Restuccia, Angela Bachi, Veronique Voisin, Gary D Bader, John E Dick, Luigi Naldini