日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling

发现一种能长期抑制下游信号的 AKT 降解剂

Inchul You, Emily C Erickson, Katherine A Donovan, Nicholas A Eleuteri, Eric S Fischer, Nathanael S Gray, Alex Toker

AICAR inhibits ceramide biosynthesis in skeletal muscle.

AICAR抑制骨骼肌中神经酰胺的生物合成

Erickson Katherine A, Smith Melissa E, Anthonymuthu Tamil S, Evanson Michael J, Brassfield Eric S, Hodson Aimee E, Bressler M Andrew, Tucker Braden J, Thatcher Mikayla O, Prince John T, Hancock Chad R, Bikman Benjamin T

Aim2 deficiency in mice suppresses the expression of the inhibitory Fcgamma receptor (FcgammaRIIB) through the induction of the IFN-inducible p202, a lupus susceptibility protein

小鼠中的 Aim2 缺乏症会通过诱导 IFN 诱导的 p202(一种狼疮易感蛋白)来抑制抑制性 Fcgamma 受体 (FcgammaRIIB) 的表达

Ravichandran Panchanathan, Hui Shen, Xin Duan, Vijay A K Rathinam, Loren D Erickson, Katherine A Fitzgerald, Divaker Choubey

Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus

Aim2 缺乏会刺激 IFN 诱导的 Ifi202 的表达,Ifi202 是 Nba2 自身免疫易感基因座内的狼疮易感鼠基因

Ravichandran Panchanathan, Xin Duan, Hui Shen, Vijay A K Rathinam, Loren D Erickson, Katherine A Fitzgerald, Divaker Choubey