Lower frequencies of circulating suppressive regulatory T cells and higher frequencies of CD4(+) naïve T cells at baseline are associated with severe immune-related adverse events in immune checkpoint inhibitor-treated melanoma
基线时循环抑制性调节性T细胞频率较低和CD4(+)幼稚T细胞频率较高与接受免疫检查点抑制剂治疗的黑色素瘤患者发生严重免疫相关不良事件有关。
期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2023-008056
Kovacsovics-Bankowski, Magdalena; Sweere, Johanna M; Healy, Connor P; Sigal, Natalia; Cheng, Li-Chun; Chronister, William D; Evans, Shane A; Marsiglio, John; Gibson, Berit; Swami, Umang; Erickson-Wayman, Alyssa; McPherson, Jordan P; Derose, Yoko S; Eliason, Annaleah Larson; Medina, Carlos O; Srinivasan, Ramji; Spitzer, Matthew H; Nguyen, Ngan; Hyngstrom, John; Hu-Lieskovan, Siwen
