日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia

急性T细胞白血病中反复出现的CTCF失活突变导致增强子-癌基因接触增强和癌基因表达水平升高。

Willem K Smits ,Carlo Vermeulen ,Rico Hagelaar ,Shunsuke Kimura ,Eric M Vroegindeweij ,Jessica G C A M Buijs-Gladdines ,Ellen van de Geer ,Marjon J A M Verstegen ,Erik Splinter ,Simon V van Reijmersdal ,Arjan Buijs ,Niels Galjart ,Winfried van Eyndhoven ,Max van Min ,Roland Kuiper ,Patrick Kemmeren ,Charles G Mullighan ,Wouter de Laat ,Jules P P Meijerink

Genetic and epigenetic features direct differential efficiency of Xist-mediated silencing at X-chromosomal and autosomal locations

遗传和表观遗传特征直接影响 Xist 介导的 X 染色体和常染色体位置沉默的差异效率

Agnese Loda, Johannes H Brandsma, Ivaylo Vassilev, Nicolas Servant, Friedemann Loos, Azadeh Amirnasr, Erik Splinter, Emmanuel Barillot, Raymond A Poot, Edith Heard, Joost Gribnau

The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA

失活的X染色体采用独特的三维构象,依赖于Xist RNA

Erik Splinter, Elzo de Wit, Elphège P Nora, Petra Klous, Harmen J G van de Werken, Yun Zhu, Lucas J T Kaaij, Wilfred van Ijcken, Joost Gribnau, Edith Heard, Wouter de Laat

Transcription and chromatin organization of a housekeeping gene cluster containing an integrated beta-globin locus control region

含有整合的 β-珠蛋白基因座控制区的管家基因簇的转录和染色质组织

Daan Noordermeer, Miguel R Branco, Erik Splinter, Petra Klous, Wilfred van Ijcken, Sigrid Swagemakers, Manousos Koutsourakis, Peter van der Spek, Ana Pombo, Wouter de Laat