日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SHIP2-PLK1 crosstalk promotes sensitivity to dual inhibition in esophageal squamous cell carcinoma

SHIP2-PLK1 相互作用促进食管鳞状细胞癌对双重抑制的敏感性

Ramos, Ana Raquel; Bregni, Giacomo; Gillet, Nadia; Ando, Kunie; Bodart, Cyril; Vercauteren Drubbel, Alizée; Descampe, Louison; Moresi, Fabiana; Bisteau, Xavier; Verheye, Quentin; Pirard, Sheleya; Erneux, Christophe; Beck, Benjamin

Loss of INPP5K attenuates IP(3)-induced Ca(2+) responses in the glioblastoma cell line U-251 MG cells.

INPP5K 的缺失会减弱胶质母细胞瘤细胞系 U-251 MG 细胞中 IP(3) 诱导的 Ca(2+) 反应

Loncke Jens, Luyten Tomas, Ramos Ana Raquel, Erneux Christophe, Bultynck Geert

The impact of phosphoinositide 5-phosphatases on phosphoinositides in cell function and human disease.

磷脂酰肌醇 5-磷酸酶对细胞功能和人类疾病中磷脂酰肌醇的影响

Ramos Ana Raquel, Ghosh Somadri, Erneux Christophe

The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases

肌醇磷酸酶SHIP2通过募集Src激酶,使FGF受体下游的ERK持续激活。

Fafilek, Bohumil; Balek, Lukas; Bosakova, Michaela Kunova; Varecha, Miroslav; Nita, Alexandru; Gregor, Tomas; Gudernova, Iva; Krenova, Jitka; Ghosh, Somadri; Piskacek, Martin; Jonatova, Lucie; Cernohorsky, Nicole H; Zieba, Jennifer T; Kostas, Michal; Haugsten, Ellen Margrethe; Wesche, Jørgen; Erneux, Christophe; Trantirek, Lukas; Krakow, Deborah; Krejci, Pavel

The Shigella type III effector IpgD recodes Ca(2+) signals during invasion of epithelial cells

志贺氏菌III型效应蛋白IpgD在侵袭上皮细胞过程中重新编码Ca(2+)信号。

Sun, Chun Hui; Wacquier, Benjamin; Aguilar, Daniel I; Carayol, Nathalie; Denis, Kevin; Boucherie, Sylviane; Valencia-Gallardo, Cesar; Simsek, Ceren; Erneux, Christophe; Lehman, Alexandre; Enninga, Jost; Arbibe, Laurence; Sansonetti, Philippe; Dupont, Geneviève; Combettes, Laurent; Tran Van Nhieu, Guy

A synthetic polyphosphoinositide headgroup surrogate in complex with SHIP2 provides a rationale for drug discovery

合成的多磷酸肌醇头基类似物与SHIP2形成复合物,为药物发现提供了理论依据。

Mills, Stephen J; Persson, Camilla; Cozier, Gyles; Thomas, Mark P; Trésaugues, Lionel; Erneux, Christophe; Riley, Andrew M; Nordlund, Pär; Potter, Barry V L

5-Stabilized phosphatidylinositol 3,4,5-trisphosphate analogues bind Grp1 PH, inhibit phosphoinositide phosphatases, and block neutrophil migration

5-稳定化的磷脂酰肌醇3,4,5-三磷酸类似物与Grp1 PH结合,抑制磷脂酰肌醇磷酸酶,并阻断中性粒细胞迁移。

Zhang, Honglu; He, Ju; Kutateladze, Tatiana G; Sakai, Takahiro; Sasaki, Takehiko; Markadieu, Nicolas; Erneux, Christophe; Prestwich, Glenn D

Benzene polyphosphates as tools for cell signalling: inhibition of inositol 1,4,5-trisphosphate 5-phosphatase and interaction with the PH domain of protein kinase Balpha

苯多磷酸酯作为细胞信号传导工具:抑制肌醇1,4,5-三磷酸5-磷酸酶并与蛋白激酶Bα的PH结构域相互作用

Mills, Stephen J; Vandeput, Fabrice; Trusselle, Melanie N; Safrany, Stephen T; Erneux, Christophe; Potter, Barry V L

Synthesis and biological activity of phosphatidylinositol-3,4,5-trisphosphorothioate

磷脂酰肌醇-3,4,5-三硫代磷酸酯的合成及生物活性

Zhang, Honglu; Xu, Yong; Markadieu, Nicolas; Beauwens, Renaud; Erneux, Christophe; Prestwich, Glenn D

The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells

人肌醇-1,4,5-三磷酸3-激酶的三种同工酶在细胞内具有特异性定位,但在转染至COS-7细胞后对Ca2+的反应却相似。

Dewaste, Valérie; Moreau, Colette; De Smedt, Florence; Bex, Françoise; De Smedt, Humbert; Wuytack, Frank; Missiaen, Ludwig; Erneux, Christophe