日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of New Virulence Factors and Vaccine Candidates for Yersinia pestis

鼠疫耶尔森菌新毒力因子及疫苗候选物的鉴定

Jourdan A Andersson, Jian Sha, Tatiana E Erova, Eric C Fitts, Duraisamy Ponnusamy, Elena V Kozlova, Michelle L Kirtley, Ashok K Chopra

Cross-talk among flesh-eating Aeromonas hydrophila strains in mixed infection leading to necrotizing fasciitis

混合感染中嗜肉气单胞菌菌株间的相互作用导致坏死性筋膜炎

Ponnusamy, Duraisamy; Kozlova, Elena V; Sha, Jian; Erova, Tatiana E; Azar, Sasha R; Fitts, Eric C; Kirtley, Michelle L; Tiner, Bethany L; Andersson, Jourdan A; Grim, Christopher J; Isom, Richard P; Hasan, Nur A; Colwell, Rita R; Chopra, Ashok K

Protective Immunity Elicited by Oral Immunization of Mice with Salmonella enterica Serovar Typhimurium Braun Lipoprotein (Lpp) and Acetyltransferase (MsbB) Mutants

小鼠口服接种鼠伤寒沙门氏菌布劳恩脂蛋白(Lpp)和乙酰转移酶(MsbB)突变体后产生的保护性免疫

Erova, Tatiana E; Kirtley, Michelle L; Fitts, Eric C; Ponnusamy, Duraisamy; Baze, Wallace B; Andersson, Jourdan A; Cong, Yingzi; Tiner, Bethany L; Sha, Jian; Chopra, Ashok K

A Replication-Defective Human Type 5 Adenovirus-Based Trivalent Vaccine Confers Complete Protection against Plague in Mice and Nonhuman Primates

基于复制缺陷型人类 5 型腺病毒的三价疫苗可为小鼠和非人类灵长类动物提供针对鼠疫的完全保护

Jian Sha, Michelle L Kirtley, Curtis Klages, Tatiana E Erova, Maxim Telepnev, Duraisamy Ponnusamy, Eric C Fitts, Wallace B Baze, Satheesh K Sivasubramani, William S Lawrence, Igor Patrikeev, Jennifer E Peel, Jourdan A Andersson, Elena V Kozlova, Bethany L Tiner, Johnny W Peterson, David McWilliams, 

Combinational deletion of three membrane protein-encoding genes highly attenuates yersinia pestis while retaining immunogenicity in a mouse model of pneumonic plague

在鼠疫模型中,三种膜蛋白编码基因的组合缺失可显著减弱鼠疫耶尔森菌的毒力,同时保留其免疫原性。

Tiner, Bethany L; Sha, Jian; Kirtley, Michelle L; Erova, Tatiana E; Popov, Vsevolod L; Baze, Wallace B; van Lier, Christina J; Ponnusamy, Duraisamy; Andersson, Jourdan A; Motin, Vladimir L; Chauhan, Sadhana; Chopra, Ashok K

Intramuscular Immunization of Mice with a Live-Attenuated Triple Mutant of Yersinia pestis CO92 Induces Robust Humoral and Cell-Mediated Immunity To Completely Protect Animals against Pneumonic Plague

用鼠疫耶尔森菌CO92活减毒三突变株进行小鼠肌肉注射免疫,可诱导强大的体液免疫和细胞免疫,从而完全保护动物免受肺鼠疫的侵害。

Tiner, Bethany L; Sha, Jian; Ponnusamy, Duraisamy; Baze, Wallace B; Fitts, Eric C; Popov, Vsevolod L; van Lier, Christina J; Erova, Tatiana E; Chopra, Ashok K

Functional genomic characterization of virulence factors from necrotizing fasciitis-causing strains of Aeromonas hydrophila

引起坏死性筋膜炎的嗜水气单胞菌菌株毒力因子的功能基因组表征

Christopher J Grim, Elena V Kozlova, Duraisamy Ponnusamy, Eric C Fitts, Jian Sha, Michelle L Kirtley, Christina J van Lier, Bethany L Tiner, Tatiana E Erova, Sandeep J Joseph, Timothy D Read, Joshua R Shak, Sam W Joseph, Ed Singletary, Tracy Felland, Wallace B Baze, Amy J Horneman, Ashok K Chopra

Deletion of Braun lipoprotein and plasminogen-activating protease-encoding genes attenuates Yersinia pestis in mouse models of bubonic and pneumonic plague

删除布朗脂蛋白和纤溶酶原激活蛋白酶编码基因可减弱鼠疫和肺鼠疫小鼠模型中的鼠疫耶尔森氏菌

Christina J van Lier, Jian Sha, Michelle L Kirtley, Anthony Cao, Bethany L Tiner, Tatiana E Erova, Yingzi Cong, Elena V Kozlova, Vsevolod L Popov, Wallace B Baze, Ashok K Chopra

The effects of modeled microgravity on growth kinetics, antibiotic susceptibility, cold growth, and the virulence potential of a Yersinia pestis ymoA-deficient mutant and its isogenic parental strain

模拟微重力对鼠疫耶尔森氏菌 ymoA 缺陷突变体及其同源亲本菌株的生长动力学、抗生素敏感性、冷生长和毒力潜力的影响

Abidat Lawal, Michelle L Kirtley, Christina J van Lier, Tatiana E Erova, Elena V Kozlova, Jian Sha, Ashok K Chopra, Jason A Rosenzweig

A non-invasive in vivo imaging system to study dissemination of bioluminescent Yersinia pestis CO92 in a mouse model of pneumonic plague

一种用于研究鼠疫耶尔森氏菌CO92在小鼠肺鼠疫模型中生物发光扩散的非侵入性体内成像系统

Sha, Jian; Rosenzweig, Jason A; Kirtley, Michelle L; van Lier, Christina J; Fitts, Eric C; Kozlova, Elena V; Erova, Tatiana E; Tiner, Bethany L; Chopra, Ashok K