The fifth transmembrane domain of angiotensin II Type 1 receptor participates in the formation of the ligand-binding pocket and undergoes a counterclockwise rotation upon receptor activation
血管紧张素II 1型受体的第五个跨膜结构域参与配体结合口袋的形成,并在受体激活后发生逆时针旋转。
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M109.051839
Domazet, Ivana; Martin, Stéphane S; Holleran, Brian J; Morin, Marie-Eve; Lacasse, Patrick; Lavigne, Pierre; Escher, Emanuel; Leduc, Richard; Guillemette, Gaétan