Breast cancer cell coculture induces normal lung fibroblast transition to CAFs, promoting tumor cell dormancy and therapy resistance
乳腺癌细胞共培养可诱导正常肺成纤维细胞向癌相关成纤维细胞(CAFs)转化,从而促进肿瘤细胞休眠和治疗耐药性。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2423894122
Klosowski, Marika L; Cronise, Kathryn E; Palmer, Eric P; McAuliffe, Kelly; Stratton, Claire; Sparks, Kelsie; Malmstrom, Kendall T; Knott-Byars, Gwyneth; Zhou, Qiong; Esquer, Hector; LaBarbera, Daniel V; Regan, Daniel P
治疗耐药
成纤维细胞
细胞生物学
乳腺癌
肿瘤
肿瘤免疫
肿瘤细胞