日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

3-(Pyridine-3-ylmethylene)chroman-4-one and tetralone derivatives: synthesis, Mycobacterium tuberculosis CYP121A1 enzyme inhibition and antimycobacterial activity vs drug-sensitive and drug-resistant strains

3-(吡啶-3-基亚甲基)色满-4-酮和四氢萘酮衍生物:合成、结核分枝杆菌CYP121A1酶抑制及抗分枝杆菌活性(针对药物敏感菌株和耐药菌株)

Alshabani, Lama A; Abdali, Jabril M; Brown, Alistair K; de Sousa, Damião Pergentino; Willcocks, Sam; Kumar, Amit; Alhejaili, Ahmed Y G; Estrada, D Fernando; Simons, Claire

NMR-guided identification of CYP11A1-Adrenodoxin interactions that differentially govern cholesterol and vitamin D3 metabolism

利用核磁共振技术鉴定CYP11A1-肾上腺皮质激素相互作用,该相互作用差异性地调控胆固醇和维生素D3代谢。

McGlohon, Janie E; Logothetis, Jacob; Estrada, D Fernando

A molecular basis of Ferredoxin Reductase (FdxR) mutations that result in mitochondriopathies

导致线粒体病的铁氧还蛋白还原酶(FdxR)突变的分子基础

Kumar, Amit; McGlohon, Janie E; Estrada, D Fernando

Active Site Residues Contribute to the Multistep Dynamics of Dicyclotyrosine Bound to CYP121A1 of Mycobacterium tuberculosis

活性位点残基参与结核分枝杆菌CYP121A1结合的二环酪氨酸的多步动力学过程

Uttamrao, Patil Pranita; Jensen, Layne J; Estrada, D Fernando; Rathinavelan, Thenmalarchelvi

Structural basis of bidirectional allostery across the heme in a cytochrome P450 enzyme

细胞色素P450酶中血红素双向变构的结构基础

Kumar, Amit; Estrada, D Fernando

(19)F-NMR reveals substrate specificity of CYP121A1 in Mycobacterium tuberculosis

(19)F-NMR揭示结核分枝杆菌CYP121A1的底物特异性

Campomizzi, Christopher S; Ghanatios, George E; Estrada, D Fernando

Crystal Structures of Drug-Metabolizing CYPs

药物代谢CYP的晶体结构

Estrada, D Fernando; Kumar, Amit; Campomizzi, Christopher S; Jay, Natalie

Structural insights into the function of steroidogenic cytochrome P450 17A1

对类固醇生成细胞色素P450 17A1功能的结构解析

Yadav, Rahul; Petrunak, Elyse M; Estrada, D Fernando; Scott, Emily E

The Structure of the Hantavirus Zinc Finger Domain is Conserved and Represents the Only Natively Folded Region of the Gn Cytoplasmic Tail

汉坦病毒锌指结构域的结构高度保守,是Gn胞质尾部唯一天然折叠的区域。

Estrada, D Fernando; Conner, Michael; Jeor, Stephen C; Guzman, Roberto N De

The Hantavirus Glycoprotein G1 Tail Contains Dual CCHC-type Classical Zinc Fingers.

汉坦病毒糖蛋白 G1 尾部含有双 CCHC 型经典锌指

Estrada D Fernando, Boudreaux Daniel M, Zhong Dalian, St Jeor Stephen C, De Guzman Roberto N