Abnormal Cholesterol Metabolism and Lysosomal Dysfunction Induce Age-Related Hearing Loss by Inhibiting mTORC1-TFEB-Dependent Autophagy
异常胆固醇代谢和溶酶体功能障碍通过抑制mTORC1-TFEB依赖性自噬诱发年龄相关性听力损失
期刊:International Journal of Molecular Sciences
影响因子:0.7
doi:10.3390/ijms242417513
Yun Yeong Lee,Jungho Ha,Young Sun Kim,Sivasubramanian Ramani,Siung Sung,Eun Sol Gil,Oak-Sung Choo,Jeong Hun Jang,Yun-Hoon Choung
代谢
MTOR
ORC1
TFEB
Autophagy
mTOR
自噬